(8-Benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-YL)-methanol

Base Information

Chemical Name:(8-Benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-YL)-methanol
CAS No.:64996-15-2
Molecular Formula:C15H21NO3
Molecular Weight:263.337
Hs Code.:2934999090
European Community (EC) Number:651-897-6
DSSTox Substance ID:DTXSID30393679
Mol file:64996-15-2.mol

Synonyms:64996-15-2;(8-BENZYL-1,4-DIOXA-8-AZA-SPIRO[4.5]DEC-6-YL)-METHANOL;(8-benzyl-1,4-dioxa-8-azaspiro[4.5]decan-6-yl)methanol;SCHEMBL5871849;DTXSID30393679;AMY14964;MFCD00183312;AKOS024330652;AB88170;AS-30051;CS-0207096;(8-benzyl-1,4-dioxa-8-azaspiro[4.5]dec-6-yl)methanol

Suppliers and Price of (8-Benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-YL)-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(8-BENZYL-1,4-DIOXA-8-AZA-SPIRO(4.5)DEC-6-YL)-METHANOL Aldrich
1ea
$ 144.00

Crysdot
(8-Benzyl-1,4-dioxa-8-azaspiro[4.5]decan-6-yl)methanol 95+%
5g
$ 582.00

Chemenu
(8-Benzyl-1,4-dioxa-8-azaspiro[4.5]decan-6-yl)methanol 96%
25g
$ 1650.00

Chemenu
(8-Benzyl-1,4-dioxa-8-azaspiro[4.5]decan-6-yl)methanol 96%
5g
$ 550.00

Chemenu
(8-Benzyl-1,4-dioxa-8-azaspiro[4.5]decan-6-yl)methanol 96%
10g
$ 918.00

Alichem
(8-Benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-yl)-methanol
25g
$ 1683.28

Alichem
(8-Benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-yl)-methanol
1g
$ 188.32

Alichem
(8-Benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-yl)-methanol
5g
$ 550.16

ACHEMBLOCK
(8-Benzyl-1,4-dioxa-8-azaspiro[4.5]decan-6-yl)methanol 95%
5G
$ 1540.00

ACHEMBLOCK
(8-Benzyl-1,4-dioxa-8-azaspiro[4.5]decan-6-yl)methanol 95%
1G
$ 385.00

Total 9 raw suppliers

Chemical Property of (8-Benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-YL)-methanol

Chemical Property:

PSA：41.93000
LogP:1.18180
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:263.15214353
Heavy Atom Count:19
Complexity:285

Purity/Quality:

95% ^*data from raw suppliers

(8-BENZYL-1,4-DIOXA-8-AZA-SPIRO(4.5)DEC-6-YL)-METHANOL Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC(C12OCCO2)CO)CC3=CC=CC=C3

Technology Process of (8-Benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-YL)-methanol

There total 4 articles about (8-Benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-YL)-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 955112-01-3
ethyl 8-benzyl-1,4-dioxa-8-azaspiro[4.5]decane-6-carboxylate

: 64996-15-2
(8-benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-yl)-methanol

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; nitrogen; water;

Reference yield:

: 64996-14-1
8-benzyl-1,4-dioxa-8-aza-spiro[4.5]decane-6-carboxylic acid methyl ester

: 64996-15-2
(8-benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-yl)-methanol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; Heating;
DOI:10.1248/cpb.25.1911

Reference yield:

: 57611-47-9
1-benzyl-4-oxo-piperidine-3-carboxylic acid methyl ester

: 64996-15-2
(8-benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-yl)-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / 2 h / 70 °C

2: LiAlH₄ / diethyl ether / Heating

With hydrogenchloride; lithium aluminium tetrahydride; In diethyl ether;
DOI:10.1248/cpb.25.1911