1H-Indole-2-carboxylic acid, 4,5,6,7-tetrahydro-3-methyl-4-oxo-, phenylmethyl ester

Base Information

Chemical Name:1H-Indole-2-carboxylic acid, 4,5,6,7-tetrahydro-3-methyl-4-oxo-, phenylmethyl ester
CAS No.:65038-89-3
Molecular Formula:C17H17NO3
Molecular Weight:283.32200
Hs Code.:

Synonyms:3-Methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid benzyl ester;Benzyl 3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate;

Suppliers and Price of 1H-Indole-2-carboxylic acid, 4,5,6,7-tetrahydro-3-methyl-4-oxo-, phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
benzyl3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate 95%
1g
$ 720.00

Alichem
Benzyl3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate
1g
$ 626.20

Total 2 raw suppliers

Chemical Property of 1H-Indole-2-carboxylic acid, 4,5,6,7-tetrahydro-3-methyl-4-oxo-, phenylmethyl ester

Chemical Property:

PSA：59.16000
LogP:3.19910

Purity/Quality:

98% ^*data from raw suppliers

benzyl3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Indole-2-carboxylic acid, 4,5,6,7-tetrahydro-3-methyl-4-oxo-, phenylmethyl ester

There total 2 articles about 1H-Indole-2-carboxylic acid, 4,5,6,7-tetrahydro-3-methyl-4-oxo-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 504-02-9
1,3-cylohexanedione

: 84080-62-6
benzyl (Z)-2-hydroxyimino-3-oxobutanoate

: 65038-89-3
benzyl 3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate

Guidance literature:: With sodium acetate; zinc; In water; acetic acid; Heating;
DOI:10.1016/S0040-4020(97)10288-5

Reference yield:

: 5396-89-4
benzyl acetoacetate

: 65038-89-3
benzyl 3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium nitrite / acetic acid; H₂O / 3 h / 10 - 20 °C

2: 43 percent / sodium acetate; zinc / acetic acid; H₂O / Heating

With sodium acetate; zinc; sodium nitrite; In water; acetic acid; 1: Nitrosation / 2: Knorr condensation;
DOI:10.1016/S0040-4020(97)10288-5