3,6-Octadecadienal, (Z,Z)-

Base Information

• Chemical Name: 3,6-Octadecadienal, (Z,Z)-
• CAS No.: 65050-43-3
• Molecular Formula: C18H32O
• Mol file: 65050-43-3.mol

Synonyms:

Chemical Property of 3,6-Octadecadienal, (Z,Z)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6-Octadecadienal, (Z,Z)-

There total 6 articles about 3,6-Octadecadienal, (Z,Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(Z,Z)-3,6-Octadecadienol (65050-40-0) → (Z,Z)-3,6-Octadecadienal (65050-43-3)

Guidance literature:

With pyridine; chromium(VI) oxide; In dichloromethane; for 2.5h; Ambient temperature; argon;

DOI:10.1021/jo00161a024

Reference yield:

bromoundecane (693-67-4) → (Z,Z)-3,6-Octadecadienal (65050-43-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) LiNH₂ / 1.) THF, O_.5 h, acetone-dry ice bath; 2.) THF, 8 h, reflux, CCl₄-dry ice bath

2: 62 percent / PBr₃, Pyridine / diethyl ether / 3 h / Heating

3: 1.) Ethylmagnesium bromide, 2.) Cuprous chloride / 1.) THF, reflux, 6 h; 2.) THF, stirred overnight, room temp.; refluxed, 9 h

4: p-toluenesulfonic acid / methanol / 2 h / Heating

5: 92 percent / H₂, ethylenediamine / P-2 Ni / ethanol / 0.42 h

6: 85 percent / anhydrous CrO₃/ pyridine / CH₂Cl₂ / 2.5 h / Ambient temperature; argon

With pyridine; chromium(VI) oxide; lithium amide; ethylmagnesium bromide; hydrogen; phosphorus tribromide; toluene-4-sulfonic acid; ethylenediamine; copper(l) chloride; P-2 Ni; In methanol; diethyl ether; ethanol; dichloromethane;

DOI:10.1021/jo00161a024

Reference yield:

1-Bromotetradec-2-yne (40924-12-7) → (Z,Z)-3,6-Octadecadienal (65050-43-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) Ethylmagnesium bromide, 2.) Cuprous chloride / 1.) THF, reflux, 6 h; 2.) THF, stirred overnight, room temp.; refluxed, 9 h

2: p-toluenesulfonic acid / methanol / 2 h / Heating

3: 92 percent / H₂, ethylenediamine / P-2 Ni / ethanol / 0.42 h

4: 85 percent / anhydrous CrO₃/ pyridine / CH₂Cl₂ / 2.5 h / Ambient temperature; argon

With pyridine; chromium(VI) oxide; ethylmagnesium bromide; hydrogen; toluene-4-sulfonic acid; ethylenediamine; copper(l) chloride; P-2 Ni; In methanol; ethanol; dichloromethane;

DOI:10.1021/jo00161a024

upstream raw materials:

(Z,Z)-3,6-Octadecadienol

bromoundecane

1-Bromotetradec-2-yne

tetradec-2-yn-1-ol