2',3'-Didehydro-3'-deoxy-4-thiothymidine

Base Information

Chemical Name:2',3'-Didehydro-3'-deoxy-4-thiothymidine
CAS No.:5983-08-4
Molecular Formula:C₁₀H₁₂N₂O₃S
Molecular Weight:240.283
Hs Code.:
DSSTox Substance ID:DTXSID30208557
Nikkaji Number:J264.460F
ChEMBL ID:CHEMBL86861
Mol file:5983-08-4.mol

Synonyms:2',3'-didehydro-3'-deoxy-4-thiothymidine;ddeTHdS

Suppliers and Price of 2',3'-Didehydro-3'-deoxy-4-thiothymidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2',3'-Didehydro-3'-deoxy-4-thiothymidine

Chemical Property:

PSA：103.15000
Density:1.45g/cm³
LogP:0.28630
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:240.05686342
Heavy Atom Count:16
Complexity:392

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN(C(=O)NC1=S)C2C=CC(O2)CO
Isomeric SMILES:CC1=CN(C(=O)NC1=S)[C@H]2C=C[C@H](O2)CO

Technology Process of 2',3'-Didehydro-3'-deoxy-4-thiothymidine

There total 4 articles about 2',3'-Didehydro-3'-deoxy-4-thiothymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 122567-98-0
5'-O-benzoyl-2',3'-didehydro-3'-deoxy-4-thiothymidine

: 5983-08-4
2',3'-didehydro-3'-deoxy-4-thiothymidine

Guidance literature:: With sodium methylate; In methanol; for 0.5h; Heating; pH 8;
DOI:10.1002/jps.2600830315

Reference yield:

: 122567-97-9
5′-benzoyl-2′,3′-didehydro-3′-deoxythymidine

: 5983-08-4
2',3'-didehydro-3'-deoxy-4-thiothymidine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / Lawesson's reagent / CHCl₃ / 4 h / Heating

2: 99 percent / CH₃ONa / methanol / 0.5 h / Heating; pH 8

With Lawessons reagent; sodium methylate; In methanol; chloroform;
DOI:10.1002/jps.2600830315

Reference yield:

: 3056-17-5
stavudin

: 5983-08-4
2',3'-didehydro-3'-deoxy-4-thiothymidine

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / pyridine / 6 h / 50 °C

2: 80 percent / Lawesson's reagent / CHCl₃ / 4 h / Heating

3: 99 percent / CH₃ONa / methanol / 0.5 h / Heating; pH 8

With Lawessons reagent; pyridine; sodium methylate; In methanol; chloroform;
DOI:10.1002/jps.2600830315