Technology Process of cis-(-)-Heptadeca-1,9-dien-4,6-diyn-3-ol
There total 10 articles about cis-(-)-Heptadeca-1,9-dien-4,6-diyn-3-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(3R)-hept-1-ene-4,6-diyn-3-ol;
With
copper(l) iodide; tetrabutyl-ammonium chloride; potassium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.25h;
(Z)-1-chlorodec-2-ene;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 8h;
Further stages.;
DOI:10.1021/jo020073w
- Guidance literature:
-
With
immobilised Candida antarctica lipase B; water;
In
acetone;
at 20 ℃;
for 43h;
pH=7.4;
optical yield given as %ee;
enantioselective reaction;
aq. phosphate buffer;
Enzymatic reaction;
DOI:10.1016/j.tet.2010.10.049
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 86 percent / H2; quinoline; KOH / Lindlar catalyst / ethanol / 16 h / atmospheric pressure
2.1: 81 percent / PPh3; CCl4 / 16 h / 80 °C
3.1: Bu4N(1+)*Cl(1-); K2CO3; CuI / dimethylformamide / 0.25 h / 20 °C
3.2: 69 percent / dimethylformamide / 8 h / 20 °C
With
quinoline; tetrachloromethane; potassium hydroxide; copper(l) iodide; tetrabutyl-ammonium chloride; hydrogen; potassium carbonate; triphenylphosphine;
Lindlar's catalyst;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jo020073w
