6-Hydroxy-2,3-dimethoxybenzaldehyde

Base Information

Chemical Name:6-Hydroxy-2,3-dimethoxybenzaldehyde
CAS No.:65162-28-9
Molecular Formula:C9H10O4
Molecular Weight:182.176
Hs Code.:
DSSTox Substance ID:DTXSID30517919
Wikidata:Q82380202

Synonyms:6-hydroxy-2,3-dimethoxybenzaldehyde;65162-28-9;Benzaldehyde, 6-hydroxy-2,3-dimethoxy-;SCHEMBL10923461;DTXSID30517919;UQWMNSCIJIOVCI-UHFFFAOYSA-N;2,3-dimethoxy-6-hydroxybenzaldehyde

Suppliers and Price of 6-Hydroxy-2,3-dimethoxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 6-Hydroxy-2,3-dimethoxybenzaldehyde

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:182.05790880
Heavy Atom Count:13
Complexity:171

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)O)C=O)OC

Technology Process of 6-Hydroxy-2,3-dimethoxybenzaldehyde

There total 4 articles about 6-Hydroxy-2,3-dimethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 66967-25-7
2-(3,4-dimethoxyphenoxy)tetrahydro-2H-pyran

: 65162-28-9
6-hydroxy-2,3-dimethoxybenzaldehyde

Guidance literature:: With lithium; In N-methyl-acetamide;

Reference yield:

: 133129-56-3
1,2-dimethoxy-4-(methoxymethoxy)benzene

: 65162-28-9
6-hydroxy-2,3-dimethoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / diethyl ether; hexane / 5 h / 0 °C / Inert atmosphere

1.2: 0 °C / Inert atmosphere

2.1: trimethylsilyl bromide / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

2.2: Inert atmosphere

With n-butyllithium; trimethylsilyl bromide; N,N,N,N,-tetramethylethylenediamine; In diethyl ether; hexane; dichloromethane;
DOI:10.1007/s11426-011-4454-0

Reference yield:

: 2033-89-8
3,4-dimethoxyphenol

: 65162-28-9
6-hydroxy-2,3-dimethoxybenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

2.1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / diethyl ether; hexane / 5 h / 0 °C / Inert atmosphere

2.2: 0 °C / Inert atmosphere

3.1: trimethylsilyl bromide / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

3.2: Inert atmosphere

With dmap; n-butyllithium; trimethylsilyl bromide; N,N,N,N,-tetramethylethylenediamine; N-ethyl-N,N-diisopropylamine; In diethyl ether; hexane; dichloromethane;
DOI:10.1007/s11426-011-4454-0