4-Aminosulphonyl-1-hydroxy-2-naphthoic acid

Base Information

Chemical Name:4-Aminosulphonyl-1-hydroxy-2-naphthoic acid
CAS No.:64415-15-2
Molecular Formula:C₁₁H₉NO₅S
Molecular Weight:267.262
Hs Code.:
European Community (EC) Number:264-882-0
NSC Number:122281
DSSTox Substance ID:DTXSID10214671
Nikkaji Number:J124.148F
Wikidata:Q83090560
ChEMBL ID:CHEMBL1410420
Mol file:64415-15-2.mol

Synonyms:NSC 122281;NSC-122281;NSC122281

Suppliers and Price of 4-Aminosulphonyl-1-hydroxy-2-naphthoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Atlantic Research Chemicals
1-Hydroxy-4-sulfamoyl-2-naphthoicacid 95%
250mgs:
$ 530.18

American Custom Chemicals Corporation
4-AMINOSULFONYL-1-HYDROXY-2-NAPHTHOIC-ACID 98.00%
10G
$ 1763.69

Total 9 raw suppliers

Chemical Property of 4-Aminosulphonyl-1-hydroxy-2-naphthoic acid

Chemical Property:

Vapor Pressure:3.74E-13mmHg at 25°C
Melting Point:225℃
Refractive Index:1.4790 (estimate)
Boiling Point:555°C at 760 mmHg
PKA:2.44±0.30(Predicted)
Flash Point:289.5°C
PSA：126.07000
Density:1.4895 (rough estimate)
LogP:2.67210
XLogP3:1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:267.02014356
Heavy Atom Count:18
Complexity:429

Purity/Quality:

99.90% ^*data from raw suppliers

1-Hydroxy-4-sulfamoyl-2-naphthoicacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes: Xi:Irritant;
Statements: R36/37/38:Irritating to eyes, respiratory system and skin.;
Safety Statements: S24/25:Avoid contact with skin and eyes.;

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CC(=C2O)C(=O)O)S(=O)(=O)N

Technology Process of 4-Aminosulphonyl-1-hydroxy-2-naphthoic acid

There total 2 articles about 4-Aminosulphonyl-1-hydroxy-2-naphthoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 60638-83-7
4-chlorosulfonyl-1-hydroxy-2-naphthoic acid

: 64415-15-2
1-hydroxy-4-sulfamoyl-2-naphthoic acid

Guidance literature:: With ammonium hydroxide; In 1,4-dioxane; at 0 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.ejmech.2016.02.006

Reference yield:

: 86-48-6
1-hydroxy-2-naphthoic acid

: 64415-15-2
1-hydroxy-4-sulfamoyl-2-naphthoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: chlorosulfonic acid / 1 h / Cooling; Inert atmosphere

2: ammonium hydroxide / 1,4-dioxane / 1 h / 0 °C / Inert atmosphere

With chlorosulfonic acid; ammonium hydroxide; In 1,4-dioxane;
DOI:10.1016/j.ejmech.2016.02.006