7,8-Dihydro-5H-pyrano[4,3-b]pyridine

Base Information

Chemical Name:7,8-Dihydro-5H-pyrano[4,3-b]pyridine
CAS No.:65210-60-8
Molecular Formula:C8H9NO
Molecular Weight:135.166
Hs Code.:
DSSTox Substance ID:DTXSID80576016
Wikidata:Q82465523

Synonyms:65210-60-8;7,8-Dihydro-5H-pyrano[4,3-b]pyridine;SCHEMBL2054541;DTXSID80576016

Suppliers and Price of 7,8-Dihydro-5H-pyrano[4,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 7,8-Dihydro-5H-pyrano[4,3-b]pyridine

Chemical Property:

Boiling Point:244.1±30.0 °C(Predicted)
PSA：22.12000
Density:1.121±0.06 g/cm3(Predicted)
LogP:1.15430
XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:135.068413911
Heavy Atom Count:10
Complexity:116

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCC2=C1N=CC=C2

Technology Process of 7,8-Dihydro-5H-pyrano[4,3-b]pyridine

There total 3 articles about 7,8-Dihydro-5H-pyrano[4,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 126473-97-0
β-(2-propynyloxy)ethylpyrazine

: 65210-60-8
7,8-dihydro-5H-pyrano[4,3-b]pyridine

: 126474-06-4
3,4-Dihydro-1H-pyrano[4,3-c]pyridine

Guidance literature:: In various solvent(s); at 195 ℃; for 19h;
DOI:10.1016/S0040-4020(01)85132-2

Reference yield:

: 1904-22-9
3-[(1-phenylprop-2-yn-1-yl)oxy]propanenitrile

: 74-86-2,25067-58-7
acetylene

: 6328-48-9
3-benzyloxypropionitrile

: 65210-60-8
7,8-dihydro-5H-pyrano[4,3-b]pyridine

: 2-(2-(benzyloxy)ethyl)pyridine

: 71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1
benzene

Guidance literature:: With triethylaluminum; cobalt(II) 2-ethylhexanoate; In toluene; at 150 ℃; for 8h; under 11400 Torr; Product distribution; reactants' ratio dependence;
DOI:10.1007/BF00954829

Reference yield:

: 6705-31-3
2-(2-hydroxyethyl)-pyrazine

: 65210-60-8
7,8-dihydro-5H-pyrano[4,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) sodium / 1.) THF, 3 h, r.t.; 2.) THF, 50 deg C, 1 h

2: 21 percent / various solvent(s) / 19 h / 195 °C

With sodium; In various solvent(s);
DOI:10.1016/S0040-4020(01)85132-2