2-Amino-3-ethoxypropanoic acid

Base Information

Chemical Name:2-Amino-3-ethoxypropanoic acid
CAS No.:4775-82-0
Molecular Formula:C₅H₁₁NO₃
Molecular Weight:133.147
Hs Code.:2922500090
DSSTox Substance ID:DTXSID90875587
Mol file:4775-82-0.mol

Synonyms:2-amino-3-ethoxypropanoic acid;122608-84-8;(s)-2-amino-3-ethoxy-propionic acid, hcl;SERINE, O-ETHYL-;o-Ethyl-l-serine;2-amino-3-ethoxypropanoicacid;SCHEMBL1532102;DTXSID90875587;AKOS011211372;(2S)-2-amino-3-ethoxy-propanoic acid;EN300-296369

Suppliers and Price of 2-Amino-3-ethoxypropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-2-Amino-3-ethoxy-propionicAcidHydrochloride
10mg
$ 45.00

Medical Isotopes, Inc.
(S)-2-Amino-3-ethoxy-propionicacid/HCl
5 g
$ 1460.00

Labseeker
(2S)-2-AMINO-3-ETHOXYPROPANOICACID 95
1g
$ 1083.00

Alfa Aesar
O-Ethoxy-L-serine hydrochloride, 97%
1g
$ 502.00

Alfa Aesar
O-Ethoxy-L-serine hydrochloride, 97%
250mg
$ 166.00

Total 12 raw suppliers

Chemical Property of 2-Amino-3-ethoxypropanoic acid

Chemical Property:

PSA：72.55000
LogP:0.93710
Water Solubility.:Soluble in water, ethanol.
XLogP3:-3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:133.07389321
Heavy Atom Count:9
Complexity:94.2

Purity/Quality:

99% ^*data from raw suppliers

(S)-2-Amino-3-ethoxy-propionicAcidHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOCC(C(=O)O)N
Uses O-Ethoxy-L-serine hydrochloride is used as a pharmaceutical intermediate.

Technology Process of 2-Amino-3-ethoxypropanoic acid

There total 1 articles about 2-Amino-3-ethoxypropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 85918-05-4
N-Trt-Ser

: 4775-82-0
(S)-2-amino-3-ethoxypropanoic acid

Guidance literature:: With acetic acid; In ethanol; for 24h; Ambient temperature;
DOI:10.1016/S0040-4020(01)88549-5

Reference yield: 90.0%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 4775-82-0
(S)-2-amino-3-ethoxypropanoic acid

: 1562432-09-0
(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-ethoxypropanoic acid

Guidance literature:: With sodium carbonate; In tetrahydrofuran; water; for 16h;

Reference yield:

: 4775-82-0
(S)-2-amino-3-ethoxypropanoic acid

: 666718-81-6
(R)-tert-butyl 1-ethoxy-3-hydroxypropan-2-ylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaOH / dioxane / 20 °C

2: NEt₃ / tetrahydrofuran / -10 °C

3: 40 percent / NaBH₄ / H₂O / 0 °C

With sodium hydroxide; sodium tetrahydroborate; triethylamine; In tetrahydrofuran; 1,4-dioxane; water;
DOI:10.1016/j.bmcl.2003.09.088