4-(1,3,4-Oxadiazol-2-yl)phenol

Base Information

Chemical Name:4-(1,3,4-Oxadiazol-2-yl)phenol
CAS No.:5378-27-8
Molecular Formula:C8H6 N2 O2
Molecular Weight:162.148
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40419854
Wikidata:Q82231070
Mol file:5378-27-8.mol

Synonyms:4-(1,3,4-oxadiazol-2-yl)phenol;5378-27-8;4-[1,3,4]Oxadiazol-2-yl-phenol;4-(1,3,4)oxadiazol-2-yl-phenol;4-(1,3,4-oxadiazolyl)phenol;4-(3H-1,3,4-oxadiazol-2-ylidene)cyclohexa-2,5-dien-1-one;Maybridge3_006494;SCHEMBL860256;DTXSID40419854;WENOJMGPELLGMA-UHFFFAOYSA-N;HMS1449H04;4-[1,3,4]Oxadiazol-2-ylphenol;MFCD00221056;ODZ100105;STK242782;4-(1,3,4)-oxadiazol-2-yl-phenol;4-(1,3,4-oxadiazol-2-yl)-phenol;4-(1,3,4-oxadiazole-2-yl)-phenol;AKOS001042376;IDI1_017881;BS-14107;BB 0238208;CS-0206835;EN300-06402;A914706;AS-871/42874599;Z56943538

Suppliers and Price of 4-(1,3,4-Oxadiazol-2-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(1,3,4-Oxadiazol-2-yl)phenol
250mg
$ 215.00

Crysdot
4-(1,3,4-Oxadiazol-2-yl)phenol 95+%
10g
$ 713.00

Crysdot
4-(1,3,4-Oxadiazol-2-yl)phenol 95+%
5g
$ 416.00

Crysdot
4-(1,3,4-Oxadiazol-2-yl)phenol 95+%
1g
$ 129.00

ChemBridge Corporation
4-(1,3,4-oxadiazol-2-yl)phenol 95%
1 g
$ 46.00

Atlantic Research Chemicals
4-(1,3,4-Oxadiazol-2-yl)phenol 95%
10mgs:
$ 49.48

Atlantic Research Chemicals
4-(1,3,4-Oxadiazol-2-yl)phenol 95%
1mg:
$ 42.41

Apolloscientific
4-(1,3,4-Oxadiazol-2-yl)phenol 98%
1g
$ 115.00

Apolloscientific
4-(1,3,4-Oxadiazol-2-yl)phenol 98%
5g
$ 345.00

Apolloscientific
4-(1,3,4-Oxadiazol-2-yl)phenol 98%
10g
$ 595.00

Total 10 raw suppliers

Chemical Property of 4-(1,3,4-Oxadiazol-2-yl)phenol

Chemical Property:

Vapor Pressure:0.152mmHg at 25°C
Boiling Point:215°Cat760mmHg
Flash Point:83.8°C
PSA：58.89000
Density:1.38g/cm³
LogP:0.12960
Storage Temp.:-20°C Freezer
Solubility.:Chloroform, Methanol
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:162.042927438
Heavy Atom Count:12
Complexity:146

Purity/Quality:

99%, ^*data from raw suppliers

4-(1,3,4-Oxadiazol-2-yl)phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NN=CO2)O
Uses 4-(1,3,4-Oxadiazol-2-yl)phenol is an intermediate in the synthesis of potential class II human histone deacetylase inhibitors.

Technology Process of 4-(1,3,4-Oxadiazol-2-yl)phenol

There total 8 articles about 4-(1,3,4-Oxadiazol-2-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 5351-23-5
4-hydroxybenzoic acid hydrazide

: 122-51-0
orthoformic acid triethyl ester

: 5378-27-8
4-(1,3,4-oxadiazol-2-yl)-phenol

Guidance literature:: for 18h; Reflux;
DOI:10.1039/c8cc05265d

Reference yield: 85.0%

: 1895-39-2
sodium chlorodifluoroacetate

: 5351-23-5
4-hydroxybenzoic acid hydrazide

: 5378-27-8
4-(1,3,4-oxadiazol-2-yl)-phenol

Guidance literature:: With potassium phosphate; In acetonitrile; at 100 ℃; for 1h; Sealed tube; Inert atmosphere;
DOI:10.1016/j.cclet.2021.08.089