1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-methoxyphenyl ester

Base Information

• Chemical Name: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-methoxyphenyl ester
• CAS No.: 65474-38-6
• Molecular Formula: C26H22ClNO5
• Molecular Weight: 463.917
• Mol file: 65474-38-6.mol

Synonyms:

Chemical Property of 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-methoxyphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-methoxyphenyl ester

There total 2 articles about 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-methoxyphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid (53-86-1) + 2-methoxy-phenol (90-05-1) → 2-methoxyphenyl[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate (65474-38-6)

Guidance literature:

[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid; With dicyclohexyl-carbodiimide; In chloroform; at 20 ℃; for 1h;

2-methoxy-phenol; With dmap; In chloroform; at 20 ℃; for 24h;

DOI:10.1007/s00044-011-9589-1

Reference yield:

→ 2-methoxyphenyl[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate (65474-38-6)

Guidance literature:

Aus der 1-p-Chlorbenzoyl-2-methyl-5-methoxy-3-indolylessigsaeure, und entspr. Alkohol; Pyridin, SOCl2;

upstream raw materials:

[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

2-methoxy-phenol