4-Oxo-alpha-(phenylmethyl)-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetic acid

Base Information

Chemical Name:4-Oxo-alpha-(phenylmethyl)-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetic acid
CAS No.:83408-94-0
Molecular Formula:C₂₆H₂₄N₂O₆
Molecular Weight:460.486
Hs Code.:2933990090
DSSTox Substance ID:DTXSID701003402
Mol file:83408-94-0.mol

Synonyms:BRN 4607403;83408-94-0;4-Oxo-alpha-(phenylmethyl)-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetic acid;3(4H)-Quinazolineacetic acid, 4-oxo-alpha-(phenylmethyl)-2-(3,4,5-trimethoxyphenyl)-;C26H24N2O6;DTXSID701003402;C26-H24-N2-O6;LS-139995;2-[4-Oxo-2-(3,4,5-trimethoxyphenyl)quinazolin-3(4H)-yl]-3-phenylpropanoic acid

Suppliers and Price of 4-Oxo-alpha-(phenylmethyl)-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-Oxo-alpha-(phenylmethyl)-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetic acid

Chemical Property:

Vapor Pressure:2.89E-18mmHg at 25°C
Boiling Point:659°Cat760mmHg
Flash Point:352.4°C
PSA：99.88000
Density:1.27g/cm³
LogP:3.95770
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:460.16343649
Heavy Atom Count:34
Complexity:738

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)C2=NC3=CC=CC=C3C(=O)N2C(CC4=CC=CC=C4)C(=O)O

Technology Process of 4-Oxo-alpha-(phenylmethyl)-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetic acid

There total 3 articles about 4-Oxo-alpha-(phenylmethyl)-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 40728-74-3
2-(3,4,5-trimethoxyphenyl)-4-H-benzo[d][1,3]oxazin-4-one

: 150-30-1,25191-15-5,658-69-5,67675-33-6
Phenylalanine

: 83408-94-0
2-[4-Oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-3-phenyl-propionic acid

Guidance literature:: In pyridine; water; for 10h; Heating;

Reference yield:

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 83408-94-0
2-[4-Oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-3-phenyl-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 1) 0-5 deg C 2) 1h, room temperature

2: 25 percent / pyridine; H₂O / 10 h / Heating

With pyridine; In pyridine; water;

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 83408-94-0
2-[4-Oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-3-phenyl-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 1) 0-5 deg C 2) 1h, room temperature

2: 25 percent / pyridine; H₂O / 10 h / Heating

With pyridine; In pyridine; water;