3-METHYL-3-P-TOLYLCYCLOPENTANONE

Base Information

• Chemical Name: 3-METHYL-3-P-TOLYLCYCLOPENTANONE
• CAS No.: 65564-92-3
• Molecular Formula: C13H16O
• Molecular Weight: 188.26600
• Mol file: 65564-92-3.mol

Synonyms:3-Methyl-3-p-tolyl-cyclopentanone;3-methyl-3-(4-methylphenyl)cyclopentanone;3-methyl-3-p-tolylcyclopentanone;

Chemical Property of 3-METHYL-3-P-TOLYLCYCLOPENTANONE

Chemical Property:

• PSA: 17.07000
• LogP: 3.00570

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-METHYL-3-P-TOLYLCYCLOPENTANONE

There total 37 articles about 3-METHYL-3-P-TOLYLCYCLOPENTANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3-Methyl-2-cyclopenten-1-one (2758-18-1) + 4-methylphenylboronic acid (5720-05-8) → 3-methyl-3-(4-methylphenyl)-cyclopentanone (65564-92-3)

Guidance literature:

With [2,2]bipyridinyl; palladium (II) trifluoroacetate; In methanol; water; at 20 - 60 ℃; for 18h; Inert atmosphere; Schlenk technique;

DOI:10.1002/cssc.201300276

Reference yield: 90.0%

C13H18O (1310492-51-3) → 3-methyl-3-(4-methylphenyl)-cyclopentanone (65564-92-3)

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 20 ℃; for 4h;

DOI:10.1080/00397911.2010.494812

Reference yield: 90.0%

methyl 2-methyl-5-oxo-2-(p-tolyl)cyclopentane-1-carboxylate → 3-methyl-3-(4-methylphenyl)-cyclopentanone (65564-92-3)

Guidance literature:

With lithium chloride; In water; dimethyl sulfoxide; at 120 ℃; for 16h;

DOI:10.1039/d0cc01017k

upstream raw materials:

3-methyl-3-(4-methylphenyl)-1-methylenecyclobutane

3-Methyl-2-cyclopenten-1-one

lithium dimethylcuprate

3-(4-Methylphenyl)-2-cyclopenten-1-one

Downstream raw materials:

α-cuparenone

(3S)-5-hydroxymethylidene-3-methyl-3-p-tolylcyclopentan-1-one

(R)-(+)-4-methyl-4-(4-methylphenyl)cyclopent-2-enone

(3S)-5-n-butylthiomethylidene-3-methyl-3-p-tolylcyclopentan-1-one