2-(4-(2-((4-Chlorophenyl)amino)-4-thiazolyl)phenoxy)propanoic acid

Base Information

Chemical Name:2-(4-(2-((4-Chlorophenyl)amino)-4-thiazolyl)phenoxy)propanoic acid
CAS No.:96928-30-2
Molecular Formula:C₁₈H₁₅ClN₂O₃S
Molecular Weight:374.848
Hs Code.:2934100090
DSSTox Substance ID:DTXSID50914249
Mol file:96928-30-2.mol

Synonyms:96928-30-2;BRN 5630207;2-(4-(2-((4-Chlorophenyl)amino)-4-thiazolyl)phenoxy)propanoic acid;Propanoic acid, 2-(4-(2-((4-chlorophenyl)amino)-4-thiazolyl)phenoxy)-;2-[4-[2-[(4-chlorophenyl)amino]-1,3-thiazol-4-yl]phenoxy]propanoic acid;DTXSID50914249;LS-121299;2-{4-[2-(4-Chloroanilino)-1,3-thiazol-4-yl]phenoxy}propanoic acid

Suppliers and Price of 2-(4-(2-((4-Chlorophenyl)amino)-4-thiazolyl)phenoxy)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(4-(2-((4-Chlorophenyl)amino)-4-thiazolyl)phenoxy)propanoic acid

Chemical Property:

Vapor Pressure:5.03E-14mmHg at 25°C
Boiling Point:574.2°Cat760mmHg
Flash Point:301.1°C
PSA：99.69000
Density:1.401g/cm³
LogP:5.13200
XLogP3:5.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:374.0491912
Heavy Atom Count:25
Complexity:440

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)O)OC1=CC=C(C=C1)C2=CSC(=N2)NC3=CC=C(C=C3)Cl

Technology Process of 2-(4-(2-((4-Chlorophenyl)amino)-4-thiazolyl)phenoxy)propanoic acid

There total 3 articles about 2-(4-(2-((4-Chlorophenyl)amino)-4-thiazolyl)phenoxy)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 96928-21-1
2-{4-[2-(4-Chloro-phenylamino)-thiazol-4-yl]-phenoxy}-propionic acid ethyl ester

: 96928-30-2
2-{4-[2-(4-Chloro-phenylamino)-thiazol-4-yl]-phenoxy}-propionic acid

Guidance literature:: With sulfuric acid; Heating;

Reference yield:

: 96928-09-5
ethyl 2-(4-acetylphenoxy)-propanoate

: 96928-30-2
2-{4-[2-(4-Chloro-phenylamino)-thiazol-4-yl]-phenoxy}-propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: Br₂, gl. acetic acid / 0.5 h / 0 °C

2: 58 percent / ethanol / Heating

3: 49 percent / 20percent aq. H₂SO₄ / Heating

With sulfuric acid; bromine; acetic acid; In ethanol;

Reference yield:

: 80099-46-3
ethyl 2-[4-(2-bromoacetyl)phenoxy]-propanoate

: 96928-30-2
2-{4-[2-(4-Chloro-phenylamino)-thiazol-4-yl]-phenoxy}-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / ethanol / Heating

2: 49 percent / 20percent aq. H₂SO₄ / Heating

With sulfuric acid; In ethanol;