2H-Isoindole-2-acetamide, N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarbonyl)-1H- 1,2,4-triazol-5-yl]methyl]-1,3-dihydro-1,3-dioxo-

Base Information

Chemical Name:2H-Isoindole-2-acetamide, N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarbonyl)-1H- 1,2,4-triazol-5-yl]methyl]-1,3-dihydro-1,3-dioxo-
CAS No.:65699-08-3
Molecular Formula:C31H24Cl2N6O5
Molecular Weight:631.475
Hs Code.:

2H-Isoindole-2-acetamide,
N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarbonyl)-1H-
1,2,4-triazol-5-yl]methyl]-1,3-dihydro-1,3-dioxo-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2H-Isoindole-2-acetamide, N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarbonyl)-1H- 1,2,4-triazol-5-yl]methyl]-1,3-dihydro-1,3-dioxo-

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Technology Process of 2H-Isoindole-2-acetamide, N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarbonyl)-1H- 1,2,4-triazol-5-yl]methyl]-1,3-dihydro-1,3-dioxo-

There total 3 articles about 2H-Isoindole-2-acetamide, N-[[1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-3-(1-pyrrolidinylcarbonyl)-1H- 1,2,4-triazol-5-yl]methyl]-1,3-dihydro-1,3-dioxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 65698-98-8
C₁₇H₁₅Cl₂N₃O₃

: 65699-08-3
1-{1-[4-chloro-2-(2-chloro-benzoyl)-phenyl]-5-[(N,N-phthaloyl-glycylamino)-methyl]-1H-[1,2,4]triazole-3-carbonyl}-pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / methanol / 96 h / Ambient temperature

2: 1) THF, hexamethylphosphoramide, r.t., 4 h, 2) acetic acid, reflux, 1.5 h

In methanol;
DOI:10.1002/jhet.5570190621

Reference yield:

: 59180-28-8
phthalylglycylglycyl chloride

: 65699-03-8
C₁₉H₁₈Cl₂N₄O₂

: 65699-08-3
1-{1-[4-chloro-2-(2-chloro-benzoyl)-phenyl]-5-[(N,N-phthaloyl-glycylamino)-methyl]-1H-[1,2,4]triazole-3-carbonyl}-pyrrolidine

Guidance literature:: Yield given. Multistep reaction; 1) THF, hexamethylphosphoramide, r.t., 4 h, 2) acetic acid, reflux, 1.5 h;
DOI:10.1002/jhet.5570190621