Methyl 4-((((4-nitrophenyl)methylene)hydrazino)sulfonyl)-3-thiophenecarboxylate

Base Information

• Chemical Name: Methyl 4-((((4-nitrophenyl)methylene)hydrazino)sulfonyl)-3-thiophenecarboxylate
• CAS No.: 145865-86-7
• Molecular Formula: C₁₃H₁₁N₃O₆S₂
• Molecular Weight: 369.379
• Mol file: 145865-86-7.mol

Synonyms:Methyl 4-((((4-nitrophenyl)methylene)hydrazino)sulfonyl)-3-thiophenecarboxylate;3-Thiophenecarboxylic acid, 4-((((4-nitrophenyl)methylene)hydrazino)sulfonyl)-, methyl ester;145865-86-7;LS-153045

Chemical Property of Methyl 4-((((4-nitrophenyl)methylene)hydrazino)sulfonyl)-3-thiophenecarboxylate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 575.5°Cat760mmHg
• Flash Point: 301.9°C
• Density: 1.55g/cm³
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 6
• Exact Mass: 369.00892743
• Heavy Atom Count: 24
• Complexity: 590

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=CSC=C1S(=O)(=O)NN=CC2=CC=C(C=C2)[N+](=O)[O-]
• Isomeric SMILES: COC(=O)C1=CSC=C1S(=O)(=O)N/N=C/C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of Methyl 4-((((4-nitrophenyl)methylene)hydrazino)sulfonyl)-3-thiophenecarboxylate

There total 2 articles about Methyl 4-((((4-nitrophenyl)methylene)hydrazino)sulfonyl)-3-thiophenecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-nitrobenzaldehdye (555-16-8) + methyl 4-(hydrazinosulfonyl)thiophene-3-carboxylate (145865-93-6) → C13H11N3O6S2 (145865-86-7)

Guidance literature:

In methanol; Heating;

Reference yield:

4-chlorosulfonylthiophene-3-carboxylic acid methyl ester (59337-85-8) → C13H11N3O6S2 (145865-86-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / 98percent hydrazine hydrate, triethylamine / ethanol / 2 h / 0 °C

2: 88 percent / methanol / Heating

With hydrazine hydrate; triethylamine; In methanol; ethanol;

upstream raw materials:

4-nitrobenzaldehdye

methyl 4-(hydrazinosulfonyl)thiophene-3-carboxylate

4-chlorosulfonylthiophene-3-carboxylic acid methyl ester