Propionic acid, 2,2,3,3-tetrafluoro-3-(trifluoromethoxy)-

Base Information

• Chemical Name: Propionic acid, 2,2,3,3-tetrafluoro-3-(trifluoromethoxy)-
• CAS No.: 377-73-1
• Molecular Formula: C4HF7O3
• Molecular Weight: 230.0378
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID70191136
• Wikidata: Q81977241
• Mol file: 377-73-1.mol

Synonyms:2,2,3,3-tetrafluoro-3-(trifluoromethoxy)propanoic acid;perfluoro-3-methoxypropanoic acid;perfluoromethoxypropionic acid;PFMOPrA perfluoro-3-methoxypropanoic acid

Chemical Property of Propionic acid, 2,2,3,3-tetrafluoro-3-(trifluoromethoxy)-

Chemical Property:

• Vapor Pressure: 7.9mmHg at 25°C
• Refractive Index: 1.286 (589.3 nm 25℃)
• Boiling Point: 124.5°Cat760mmHg
• PKA: 0.52±0.10(Predicted)
• Flash Point: 29.1°C
• PSA: 46.53000
• Density: 1.718g/cm³
• LogP: 1.83550
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 3
• Exact Mass: 229.98139102
• Heavy Atom Count: 14
• Complexity: 232

Purity/Quality:

NLT 98% ^*data from raw suppliers

Perfluoro-3-methoxypropanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: PFAS
• Canonical SMILES: C(=O)(C(C(OC(F)(F)F)(F)F)(F)F)O

Technology Process of Propionic acid, 2,2,3,3-tetrafluoro-3-(trifluoromethoxy)-

There total 3 articles about Propionic acid, 2,2,3,3-tetrafluoro-3-(trifluoromethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

perfluoro-3-methoxypropionyl fluoride (425-38-7) → perfluoro(3-oxabutanoic) acid (377-73-1)

Guidance literature:

With potassium hydroxide;

Reference yield:

C8F14O6 (79754-25-9) → perfluoro(3-oxabutanoic) acid (377-73-1)

Guidance literature:

In 1,1,2-Trichloro-1,2,2-trifluoroethane; water; at 30 ℃; Kinetics; Thermodynamic data; Mechanism; other temperature, ΔS(excit.), other solvent;

Reference yield:

→ perfluoro(3-oxabutanoic) acid (377-73-1)

Guidance literature:

entspr. Saeurefluorid, Hydrol.;

upstream raw materials:

perfluoro-3-methoxypropionyl fluoride

C₈F₁₄O₆

Downstream raw materials:

1-phenyl-2,2,3,3,5,5,5-heptafluoro-4-oxapentan-1-one

silver perfluoromethoxybutyrate

methyl 4-oxaperfluoropentanoate

Refernces