4-(3-Methoxyphenyl)quinolin-2(1H)-one

Base Information

Chemical Name:4-(3-Methoxyphenyl)quinolin-2(1H)-one
CAS No.:65848-66-0
Molecular Formula:C16H13NO2
Molecular Weight:251.285
Hs Code.:
DSSTox Substance ID:DTXSID70576787
Nikkaji Number:J2.392.948A
Wikidata:Q82466651

Synonyms:65848-66-0;4-(3-Methoxyphenyl)quinolin-2(1H)-one;SCHEMBL8987324;DTXSID70576787

Suppliers and Price of 4-(3-Methoxyphenyl)quinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(3-Methoxyphenyl)quinolin-2(1H)-one

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:377

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2=CC(=O)NC3=CC=CC=C32

Technology Process of 4-(3-Methoxyphenyl)quinolin-2(1H)-one

There total 13 articles about 4-(3-Methoxyphenyl)quinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 124-38-9,18923-20-1
carbon dioxide

: 574724-16-6
m-methoxyacetophenone p-toluenesulfonylhydrazone

: 615-43-0
2-iodophenylamine

: 65848-66-0
4-(3-methoxyphenyl)-1H-quinolin-2-one

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium t-butanolate; In diethylene glycol dimethyl ether; at 140 ℃; for 24h; under 760.051 Torr; Glovebox; Schlenk technique; Inert atmosphere;
DOI:10.1002/chem.201604256

Reference yield: 65.0%

: 952340-26-0
(E)-3-(2-bromophenyl)acrylamide

: 766-85-8
3-methoxy-1-iodobenzene

: 65848-66-0
4-(3-methoxyphenyl)-1H-quinolin-2-one

Guidance literature:: With tetrabutylammomium bromide; tetrabutylammonium acetate; palladium diacetate; at 120 ℃; for 36h;
DOI:10.1002/adsc.200600342