Cefminox

Base Information

Chemical Name:Cefminox
CAS No.:84305-41-9
Deprecated CAS:75481-73-1,97162-19-1
Molecular Formula:C₁₆H₂₁N₇O₇S₃
Molecular Weight:519.583
Hs Code.:
UNII:PW08Y13465
DSSTox Substance ID:DTXSID301016174
Nikkaji Number:J22.938E
Wikipedia:Cefminox
Wikidata:Q5057239
NCI Thesaurus Code:C76169
Metabolomics Workbench ID:152118
ChEMBL ID:CHEMBL1276342

Synonyms:Alteporina;cefminox;cefminox sodium;MT 141;MT-141;Tencef

Suppliers and Price of Cefminox

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AvaChem
Cefminox
1g
$ 290.00

AvaChem
Cefminox
100mg
$ 79.00

AvaChem
Cefminox
25mg
$ 49.00

AvaChem
Cefminox
10mg
$ 39.00

Total 6 raw suppliers

Chemical Property of Cefminox

Chemical Property:

PKA:2.05±0.10(Predicted)
PSA：278.76000
Density:1.86±0.1 g/cm3(Predicted)
LogP:-0.81090
XLogP3:-4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:11
Exact Mass:519.06645956
Heavy Atom Count:33
Complexity:862

Purity/Quality:

99%, ^*data from raw suppliers

Cefminox ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)(NC(=O)CSCC(C(=O)O)N)OC)SC2)C(=O)O
Isomeric SMILES:CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)CSC[C@H](C(=O)O)N)OC)SC2)C(=O)O

Technology Process of Cefminox

There total 5 articles about Cefminox which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.14%

: 7β-amino-7α-methoxy-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid

: 32443-99-5
D-cysteine hydrochloride

: 598-21-0
2-Bromoacetyl bromide

: 84305-41-9,97162-19-1
cefminox sodium

Guidance literature:: 7β-amino-7α-methoxy-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid; With triethylamine; In dichloromethane; at -5 ℃; Inert atmosphere;

2-Bromoacetyl bromide; In dichloromethane; at -65 - -25 ℃; Inert atmosphere;

D-cysteine hydrochloride; With ammonium chloride; In water; at 20 ℃; for 4h;

Reference yield:

: 921-01-7
D-cysteine

: (7R)-7-(2-bromoacetamido)-7-methoxy-3-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

: 84305-41-9,97162-19-1
cefminox

Guidance literature:: With sodium hydrogencarbonate; In water; at 20 ℃; for 2h; pH=6.5; pH-value; Solvent;

Reference yield:

: diphenylmethyl (6R,7S)-7-amino-7-methoxy-3-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

: 84305-41-9,97162-19-1
cefminox

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane; N,N-dimethyl-aniline / 0.33 h / 8 °C

2: phosphoric acid supported activated carbon / water / 0.5 h / 30 °C

3: sodium hydrogencarbonate / water / 2 h / 20 °C / pH 6.5

With sodium hydrogencarbonate; In dichloromethane; water; N,N-dimethyl-aniline;