Mofegiline hydrochloride

Base Information

• Chemical Name: Mofegiline hydrochloride
• CAS No.: 120635-25-8
• Molecular Formula: C11H13F2N.ClH
• Molecular Weight: 233.689
• UNII: 08331R10RY
• Wikidata: Q27236357
• NCI Thesaurus Code: C80965
• ChEMBL ID: CHEMBL2106694
• Mol file: 120635-25-8.mol

Synonyms:4-fluoro-beta-(fluoromethylene)benzenebutanamine;MDL 72974;MDL-72,974;MDL-72974A;mofegiline

Chemical Property of Mofegiline hydrochloride

Chemical Property:

• Vapor Pressure: 0.00232mmHg at 25°C
• Melting Point: 131°
• Boiling Point: 288.6 °C at 760 mmHg
• Flash Point: 165.3 °C
• PSA: 26.02000
• LogP: 4.07270
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 233.0782835
• Heavy Atom Count: 15
• Complexity: 184

Purity/Quality:

99% ^*data from raw suppliers

Mofegilinehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CCC(=CF)CN)F.Cl
• Isomeric SMILES: C1=CC(=CC=C1CC/C(=C\F)/CN)F.Cl
• Uses: Antiparkinsonian.

Technology Process of Mofegiline hydrochloride

There total 2 articles about Mofegiline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-N-(2-(fluoromethylene)-4-(p-fluorophenyl)butyl)-N-formyl formamide (177031-49-1) → MDL 72,794 (120635-25-8)

Guidance literature:

With hydrogenchloride; concentrated aqueous hydrochloric acid; In ethanol; Isopropyl acetate; water; toluene;

Reference yield:

→ MDL 72,794 (120635-25-8)

Guidance literature:

upstream raw materials:

(E)-N-(2-(fluoromethylene)-4-(p-fluorophenyl)butyl)-N-formyl formamide

Refernces

• 1、 -. "Process for the preparation of (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, novel processes for preparing an intermediate thereof, and novel intermediates thereof". . . Retrieved 2008/06/13.