1-methyl-1H-indene-2-carboxylic acid

Base Information

Chemical Name:1-methyl-1H-indene-2-carboxylic acid
CAS No.:66130-41-4
Molecular Formula:C11H10O2
Molecular Weight:174.19600
Hs Code.:
DSSTox Substance ID:DTXSID90496357

Synonyms:1-methyl-1H-indene-2-carboxylic acid;66130-41-4;3-methyl-indene-2-carboxylic acid;1H-Indene-2-carboxylic acid, 1-methyl-;1-methyl-2-carboxyindene;SCHEMBL3312303;DTXSID90496357;FCYXPVYPQBAIJT-UHFFFAOYSA-N;1-methyl-1H-indene-2-carboxylicacid;AKOS015964542;CS-0239521;FT-0694655;EN300-214372

Suppliers and Price of 1-methyl-1H-indene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-methyl-1H-indene-2-carboxylicacid
5mg
$ 45.00

AK Scientific
1-Methyl-1H-indene-2-carboxylicacid
500mg
$ 851.00

AK Scientific
1-Methyl-1H-indene-2-carboxylicacid
250mg
$ 576.00

Total 5 raw suppliers

Chemical Property of 1-methyl-1H-indene-2-carboxylic acid

Chemical Property:

Vapor Pressure:0.000168mmHg at 25°C
Melting Point:169-170 °C
Boiling Point:316.8oC at 760 mmHg
PKA:4.69±0.40(Predicted)
Flash Point:145.8oC
PSA：37.30000
Density:1.226g/cm3
LogP:2.27170
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:174.068079557
Heavy Atom Count:13
Complexity:255

Purity/Quality:

99% ^*data from raw suppliers

1-methyl-1H-indene-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C2=CC=CC=C2C=C1C(=O)O

Technology Process of 1-methyl-1H-indene-2-carboxylic acid

There total 5 articles about 1-methyl-1H-indene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 66130-40-3
1-Methyl-inden-2-carbonsaeure-methylester

: 66130-41-4
(+/-)-1-methylindene-2-carboxylic acid

Guidance literature:: With trichloromethyl silane; sodium iodide; In acetonitrile;
DOI:10.1016/S0957-4166(99)00576-5

Reference yield:

: 6072-57-7,22573-38-2
3-methylindanone

: 66130-41-4
(+/-)-1-methylindene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / NaH / benzene / 4 h / 80 °C

2: 100 percent Chromat_. / NaBH₄ / methanol / 4 h

3: pTsOH*H₂O / benzene / 4 h / Heating

4: trichloromethylsilane; NaI / acetonitrile

With sodium tetrahydroborate; trichloromethyl silane; sodium hydride; toluene-4-sulfonic acid; sodium iodide; In methanol; acetonitrile; benzene; 1: Condensation / 2: Reduction / 3: Dehydration / 4: Hydrolysis;
DOI:10.1016/S0957-4166(99)00576-5

Reference yield:

: 66130-38-9
1-methyl-3-oxo-indan-2-carboxylic acid methyl ester

: 66130-41-4
(+/-)-1-methylindene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent Chromat_. / NaBH₄ / methanol / 4 h

2: pTsOH*H₂O / benzene / 4 h / Heating

3: trichloromethylsilane; NaI / acetonitrile

With sodium tetrahydroborate; trichloromethyl silane; toluene-4-sulfonic acid; sodium iodide; In methanol; acetonitrile; benzene; 1: Reduction / 2: Dehydration / 3: Hydrolysis;
DOI:10.1016/S0957-4166(99)00576-5