7-(Aminomethyl)-5-chloroquinolin-8-ol dihydrochloride

Base Information

Chemical Name:7-(Aminomethyl)-5-chloroquinolin-8-ol dihydrochloride
CAS No.:66233-86-1
Molecular Formula:C10H9ClN2O.2ClH
Molecular Weight:245.10500
Hs Code.:2922390090
European Community (EC) Number:870-076-5
Mol file:66233-86-1.mol

Synonyms:7-(aminomethyl)-5-chloroquinolin-8-ol dihydrochloride;66233-86-1;7-(Aminomethyl)-5-chloroquinolin-8-ol 2HCl;MFCD27501037;7-(aminomethyl)-5-chloroquinolin-8-ol;dihydrochloride;C10H11Cl3N2O;7-(Aminomethyl)-5-chloro-quinolin-8-ol dihydrochloride;SCHEMBL11663296;AMY5472;CS3210;AKOS024462817;SB69698;AS-46628;EN300-258669;7-(aminomethyl)-5-chloroquinolin-8-oldihydrochloride;F2197-0182;Z2696918790

Suppliers and Price of 7-(Aminomethyl)-5-chloroquinolin-8-ol dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
7-(Aminomethyl)-5-chloroquinolin-8-oldihydrochloride 95+%
250mg
$ 8499.00

AK Scientific
7-(Aminomethyl)-5-chloroquinolin-8-oldihydrochloride
10g
$ 3164.00

AK Scientific
7-(Aminomethyl)-5-chloroquinolin-8-oldihydrochloride
5g
$ 2165.00

AK Scientific
7-(Aminomethyl)-5-chloroquinolin-8-oldihydrochloride
1g
$ 812.00

Total 5 raw suppliers

Chemical Property of 7-(Aminomethyl)-5-chloroquinolin-8-ol dihydrochloride

Chemical Property:

PSA：59.14000
LogP:3.55480
Storage Temp.:Inert atmosphere,Room Temperature
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:279.993696
Heavy Atom Count:16
Complexity:203

Purity/Quality:

99%, ^*data from raw suppliers

7-(Aminomethyl)-5-chloroquinolin-8-oldihydrochloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C(C(=C2N=C1)O)CN)Cl.Cl.Cl

Technology Process of 7-(Aminomethyl)-5-chloroquinolin-8-ol dihydrochloride

There total 3 articles about 7-(Aminomethyl)-5-chloroquinolin-8-ol dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61627-00-7
5-chloro-7-(phthalimidomethyl)-8-quinolinol

: 66233-86-1
7-(aminomethyl)-5-chloro-8-quinolinol dihydochloride

Guidance literature:: With hydrogenchloride; for 52h; Heating;
DOI:10.1021/jm00358a023

Reference yield:

: 130-16-5
5-Chloro-8-hydroxyquinoline

: 66233-86-1
7-(aminomethyl)-5-chloro-8-quinolinol dihydochloride

Guidance literature:: Multi-step reaction with 2 steps

1: concd. H₂SO₄ / 25 h / Heating

2: 15.5 g / concd. HCl / 52 h / Heating

With hydrogenchloride; sulfuric acid;
DOI:10.1021/jm00358a023