1-Iodo-7-methoxynaphthalene

Base Information

• Chemical Name: 1-Iodo-7-methoxynaphthalene
• CAS No.: 66240-21-9
• Molecular Formula: C11H9IO
• Molecular Weight: 284.096
• DSSTox Substance ID: DTXSID50597273
• Wikidata: Q82492784
• Mol file: 66240-21-9.mol

Synonyms:1-Iodo-7-methoxynaphthalene;66240-21-9;Naphthalene, 1-iodo-7-methoxy-;SCHEMBL9037894;DTXSID50597273;DB-073723;A19034

Chemical Property of 1-Iodo-7-methoxynaphthalene

Chemical Property:

• PSA: 9.23000
• LogP: 3.45300
• Storage Temp.: 2-8°C
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 283.96981
• Heavy Atom Count: 13
• Complexity: 172

Purity/Quality:

97% ^*data from raw suppliers

1-iodo-7-methoxynaphthalene 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC2=C(C=CC=C2I)C=C1

Technology Process of 1-Iodo-7-methoxynaphthalene

There total 6 articles about 1-Iodo-7-methoxynaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-iodo-7-hydroxynaphthalene (29921-51-5) + dimethyl sulfate (77-78-1) → 1-iodo-7-methoxynaphthalene (66240-21-9)

Guidance literature:

1-iodo-7-hydroxynaphthalene; With potassium carbonate; In acetone; at 20 ℃; for 0.25h;

dimethyl sulfate; In acetone; at 20 ℃; for 3h;

DOI:10.1016/j.tetlet.2012.10.077

Reference yield: 95.0%

C15H20O2Si → 1-iodo-7-methoxynaphthalene (66240-21-9)

Guidance literature:

With chloro-trimethyl-silane; sodium iodide; In acetonitrile; at 0 - 20 ℃; for 1.16667h;

DOI:10.1002/asia.201801454

Reference yield: 80.0%

7-methoxynaphthalen-1-amine (5302-79-4) → 1-iodo-7-methoxynaphthalene (66240-21-9)

Guidance literature:

With toluene-4-sulfonic acid; potassium iodide; sodium nitrite; In acetonitrile; at 0 - 20 ℃; for 2h;

upstream raw materials:

7-methoxynaphthalen-1-amine

N-(7-methoxynaphthalen-1-yl)acetamide

1-acetylamino-7-naphthol

1-iodo-7-hydroxynaphthalene

Downstream raw materials:

1-cyano-7-methoxynaphthalene

7-methoxynaphthalene-1-carbaldehyde

2-(7-methoxynaphth-1-yl)ethylamine

agomelatine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 66240-21-9 1-Iodo-7-methoxynaphthalene

Send

Send

Metric Ton KG G Pound L ML

Send

Send