3'-Cytidylic acid, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, mono(4-chlorophenyl) ester

Base Information Edit

Chemical Name:3'-Cytidylic acid, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, mono(4-chlorophenyl) ester
CAS No.:66274-77-9
Molecular Formula:C43H39ClN3O10P
Molecular Weight:824.224
Hs Code.:
Mol file:66274-77-9.mol

Synonyms:

Suppliers and Price of 3'-Cytidylic acid, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, mono(4-chlorophenyl) ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3'-Cytidylic acid, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, mono(4-chlorophenyl) ester Edit

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3'-Cytidylic acid, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, mono(4-chlorophenyl) ester

There total 6 articles about 3'-Cytidylic acid, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, mono(4-chlorophenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67219-55-0
4-N-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine

: 772-79-2
4-chlorophenylphosphorodichloridate

: 66274-77-9
4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)-N⁴-benzoyl-2'-deoxycytidin-3'-yl phosphate

Guidance literature:: With 1,2,3-triazole; triethylamine; In 1,4-dioxane; pyridine; 1.) 0 deg C, 1 h; 2.) room temp., 1 h;
DOI:10.1248/cpb.30.3951

Reference yield:

: C₄₃H₃₉ClN₃O₉P

: 66274-77-9
4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)-N⁴-benzoyl-2'-deoxycytidin-3'-yl phosphate

Guidance literature:: C₄₃H₃₉ClN₃O₉P; With iodine; In dichloromethane; for 0.00555556h;

With water; In dichloromethane; for 0.0833333h;

Reference yield:

: 110237-98-4
5'-(4,4'-dimethoxytrityl)-N⁴-benzoyl-2'-deoxycytidine-3'-H-phosphonate

: 66274-77-9
4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)-N⁴-benzoyl-2'-deoxycytidin-3'-yl phosphate

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine; diphenyl phosphorochloridate / CH₂Cl₂ / 0.25 h

2.1: I₂ / CH₂Cl₂ / 0.01 h

2.2: 0.384 g / H₂O / CH₂Cl₂ / 0.08 h

With pyridine; iodine; chlorophosphoric acid diphenyl ester; In dichloromethane;