2-(Hydroxymethyl)-5-(6-piperidin-1-ylpurin-9-yl)oxolane-3,4-diol

Base Information

Chemical Name:2-(Hydroxymethyl)-5-(6-piperidin-1-ylpurin-9-yl)oxolane-3,4-diol
CAS No.:41552-92-5
Molecular Formula:C₁₅H₂₁N₅O₄
Molecular Weight:335.363
Hs Code.:
NSC Number:105828
DSSTox Substance ID:DTXSID30295861
ChEMBL ID:CHEMBL1872317
Mol file:41552-92-5.mol

Synonyms:MLS002703852;41552-92-5;NSC105828;Oprea1_229170;CHEMBL1872317;SCHEMBL13170054;DTXSID30295861;NSC-105828;SMR001570566

Suppliers and Price of 2-(Hydroxymethyl)-5-(6-piperidin-1-ylpurin-9-yl)oxolane-3,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-(Hydroxymethyl)-5-(6-piperidin-1-ylpurin-9-yl)oxolane-3,4-diol

Chemical Property:

Vapor Pressure:4.81E-18mmHg at 25°C
Boiling Point:654.9°Cat760mmHg
Flash Point:349.9°C
Density:1.72g/cm³
XLogP3:0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:335.15935417
Heavy Atom Count:24
Complexity:438

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C2=NC=NC3=C2N=CN3C4C(C(C(O4)CO)O)O

Technology Process of 2-(Hydroxymethyl)-5-(6-piperidin-1-ylpurin-9-yl)oxolane-3,4-diol

There total 10 articles about 2-(Hydroxymethyl)-5-(6-piperidin-1-ylpurin-9-yl)oxolane-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 80585-34-8
9-(2,3,5-tri-Ο-acetyl-1β-D-ribofuranosyl)-6-(piperidin-1-yl)-9H-purine

: 41552-92-5
6-(piperidin-1-yl)-9-(β-D-ribofuranosyl)purine

Guidance literature:: With sodium methylate; In methanol; at 20 ℃; for 1h;
DOI:10.1016/j.bmc.2012.07.037

Reference yield: 91.0%

: 110-89-4
piperidine

: 2004-06-0
6-Chloropurine riboside

: 41552-92-5
6-(piperidin-1-yl)-9-(β-D-ribofuranosyl)purine

Guidance literature:: 6-Chloropurine riboside; With (1,3,5-triaza-7-phosphaadamantan-1-ium-1-yl)butane-1-sulfonate; palladium diacetate; In N,N-dimethyl-formamide; for 0.0833333h; Schlenk technique; Inert atmosphere;

piperidine; With triethylamine; In N,N-dimethyl-formamide; at 23 ℃; for 4h; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.7b03854