7-Methoxy-2,2-dimethyl-2H-chromen-5-amine hydrochloride

Base Information

Chemical Name:7-Methoxy-2,2-dimethyl-2H-chromen-5-amine hydrochloride
CAS No.:66385-03-3
Molecular Formula:C12H15NO2.ClH
Molecular Weight:241.718
Hs Code.:
DSSTox Substance ID:DTXSID50561439

Synonyms:66385-03-3;7-Methoxy-2,2-dimethyl-2H-chromen-5-amine hydrochloride;DTXSID50561439;7-methoxy-2,2-dimethylchromen-5-amine;hydrochloride;7-Methoxy-2,2-dimethyl-2H-chromen-5-aminehydrochloride;7-Methoxy-2,2-dimethyl-2H-1-benzopyran-5-amine--hydrogen chloride (1/1)

Suppliers and Price of 7-Methoxy-2,2-dimethyl-2H-chromen-5-amine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 7-Methoxy-2,2-dimethyl-2H-chromen-5-amine hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:241.0869564
Heavy Atom Count:16
Complexity:262

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C=CC2=C(C=C(C=C2O1)OC)N)C.Cl

Technology Process of 7-Methoxy-2,2-dimethyl-2H-chromen-5-amine hydrochloride

There total 4 articles about 7-Methoxy-2,2-dimethyl-2H-chromen-5-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 67015-37-6
6-bromo-7-methoxy-2,2-dimethyl-2H-chromene

: 66385-03-3
5-amino-7-methoxy-2,2-dimethyl-2H-chromene hydrochloride

Guidance literature:: With hydrogenchloride; ammonium chloride; sodium amide; 1.) liquid ammonia, -78 deg C, 20 h; 2.) ether;

Reference yield:

: 20321-73-7
7-methoxy-2,2-dimethyl-4-chromanone

: 66385-03-3
5-amino-7-methoxy-2,2-dimethyl-2H-chromene hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / N-bromosuccinimide / CH₂Cl₂ / 24 h / Ambient temperature

2: 95 percent / LiAlH₄ / tetrahydrofuran / 1 h / Ambient temperature

3: 96 percent / POCl₃, pyridine / toluene / 2 h / Ambient temperature

4: 65 percent / 1.) sodium amide, NH₄Cl; 2.) gaseous hydrochlorid acid / 1.) liquid ammonia, -78 deg C, 20 h; 2.) ether

With pyridine; hydrogenchloride; N-Bromosuccinimide; lithium aluminium tetrahydride; ammonium chloride; sodium amide; trichlorophosphate; In tetrahydrofuran; dichloromethane; toluene;

Reference yield:

: 69309-20-2
6-bromo-7-methoxy-2,2-dimethylchroman-4-one

: 66385-03-3
5-amino-7-methoxy-2,2-dimethyl-2H-chromene hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / LiAlH₄ / tetrahydrofuran / 1 h / Ambient temperature

2: 96 percent / POCl₃, pyridine / toluene / 2 h / Ambient temperature

3: 65 percent / 1.) sodium amide, NH₄Cl; 2.) gaseous hydrochlorid acid / 1.) liquid ammonia, -78 deg C, 20 h; 2.) ether

With pyridine; hydrogenchloride; lithium aluminium tetrahydride; ammonium chloride; sodium amide; trichlorophosphate; In tetrahydrofuran; toluene;