Benzeneethanamine, 4-(phenylmethoxy)-, hydrochloride

Base Information

• Chemical Name: Benzeneethanamine, 4-(phenylmethoxy)-, hydrochloride
• CAS No.: 2982-54-9
• Molecular Formula: C15H17 N O . Cl H
• Molecular Weight: 263.767
• DSSTox Substance ID: DTXSID90183957
• Mol file: 2982-54-9.mol

Synonyms:2982-54-9;4-benzyloxy-phenethylamine hcl;2-(4-(benzyloxy)phenyl)ethanamine hydrochloride;Benzeneethanamine, 4-(phenylmethoxy)-, hydrochloride;2-[4-(benzyloxy)phenyl]ethan-1-amine hydrochloride;2-(4-benzyloxy-phenyl)-ethylamine hydrochloride;4-(Phenylmethoxy)benzeneethanamine hydrochloride;2-(4-phenylmethoxyphenyl)ethanamine;hydrochloride;4-benzyloxy-phenethylamine hydrochloride;2-(4-Benzyloxy-phenyl)-ethylamine, HCl;2-(4-phenylmethoxyphenyl)ethanamine hydrochloride;C15H17NO.ClH;SCHEMBL4449735;DTXSID90183957;CAA98254;4-(Benzyloxy)-benzeneethanamine HCl;MFCD01657171;4-Benzyloxyphenethylamine hydrochloride;AKOS016901026;2-(4-(benzyloxy)phenyl)ethanamine HCl;AS-36330;LS-30224;CS-0156171;EN300-42426;A820068;J-017661;Z431531600;2-(4-benzyloxyphenyl)ethanamine hydrochloride;4-BENZYLOXY-PHENETHYLAMINE HCL;4-BENZYLOXY-3-AMINO-A-[-BENZYL-N-(1-METHYL-2P-METHOXY PHENYL ETHER) AMINO-METHYL BENZYL ALCOHOL;4-Benzyloxy-3-amino-a-[-benzyl-N-(1-methyl-2p-methoxy phenyl ether)amino-methyl benzyl alcohol

Chemical Property of Benzeneethanamine, 4-(phenylmethoxy)-, hydrochloride

Chemical Property:

• Vapor Pressure: 1.1E-05mmHg at 25°C
• Melting Point: 196-206 °C (decomp)
• Boiling Point: 370.5°C at 760 mmHg
• Flash Point: 179.6°C
• PSA: 35.25000
• LogP: 4.26910
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 263.1076919
• Heavy Atom Count: 18
• Complexity: 193

Purity/Quality:

97% ^*data from raw suppliers

2-(4-(Benzyloxy)phenyl)ethanaminehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC=C(C=C2)CCN.Cl

Technology Process of Benzeneethanamine, 4-(phenylmethoxy)-, hydrochloride

There total 11 articles about Benzeneethanamine, 4-(phenylmethoxy)-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-(tert-butoxycarbonyl)-2-[4-(benzyloxy)phenyl]ethylamine (182921-01-3) → 2-[4-(benzyloxy)phenyl]ethylamine hydrochloride (2982-54-9)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃;

DOI:10.1021/jm0505718

Reference yield: 94.0%

→ 2-[4-(benzyloxy)phenyl]ethylamine hydrochloride (2982-54-9)

Guidance literature:

With hydrogenchloride; In methanol; at 25 ℃; for 1h;

Reference yield: 42.0%

2-[4-(benzyloxy)phenyl]acetonitrile (838-96-0) → 2-[4-(benzyloxy)phenyl]ethylamine hydrochloride (2982-54-9)

Guidance literature:

2-[4-(benzyloxy)phenyl]acetonitrile; With sodium tetrahydroborate; trifluoroacetic acid; In tetrahydrofuran; at 20 ℃; for 4h; Cooling with ice;

With hydrogenchloride; In methanol;

upstream raw materials:

1-(2'-azidoethyl)-4-(benzyloxy)benzene

N-(tert-butoxycarbonyl)-2-[4-(benzyloxy)phenyl]ethylamine

tyrosamine

N-t-butoxycarbonyl-tyramine

Downstream raw materials:

N-(4-(benzyloxy)phenethyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxamide

(2S,3R,3aS,12bR)-1,2,3,3a,4,5,7,8-octahydro-11-benzyloxy-2-methyl-5-oxo-cyclopenta[2,3]pyrrolo[2,1-a]isoquinoline-3-carboxylic acid

(2S,3R,3aS,12bR)-1,2,3,3a,4,5,7,8-octahydro-11-benzyloxy-2-methyl-3-nitromethyl-5-oxo-cyclopenta[2,3]pyrrolo[2,1-a]isoquinoline

2-(4-(benzyloxy)phenyl)ethanamine