N-[(3Z)-3-(Hydroxyimino)-1-phenylbutan-2-yl]acetamide

Base Information

Chemical Name:N-[(3Z)-3-(Hydroxyimino)-1-phenylbutan-2-yl]acetamide
CAS No.:6955-09-5
Molecular Formula:C12H16N2O2
Molecular Weight:220.2676
Hs Code.:
NSC Number:20141
DSSTox Substance ID:DTXSID20417858

Synonyms:6955-09-5;DTXSID20417858;NSC20141;NSC-20141;N-[(3Z)-3-(Hydroxyimino)-1-phenylbutan-2-yl]acetamide

Suppliers and Price of N-[(3Z)-3-(Hydroxyimino)-1-phenylbutan-2-yl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N-[(3Z)-3-(Hydroxyimino)-1-phenylbutan-2-yl]acetamide

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:475.6°Cat760mmHg
Flash Point:241.5°C
Density:1.1g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:220.121177757
Heavy Atom Count:16
Complexity:258

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=NO)C(CC1=CC=CC=C1)NC(=O)C
Isomeric SMILES:C/C(=N/O)/C(CC1=CC=CC=C1)NC(=O)C

Technology Process of N-[(3Z)-3-(Hydroxyimino)-1-phenylbutan-2-yl]acetamide

There total 2 articles about N-[(3Z)-3-(Hydroxyimino)-1-phenylbutan-2-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 142924-43-4
(S)-N-(3-oxo-1-phenylbutan-2-yl)acetamide

: 6955-09-5
N-{(S)-1-Benzyl-2-[(Z)-hydroxyimino]-propyl}-acetamide

Guidance literature:: With sodium acetate; In water; at 60 - 80 ℃; for 2h;
DOI:10.1016/S0040-4039(01)82927-0

Reference yield:

: 2018-61-3
(S)-2-acetylamino-3-phenylpropanoic acid

: 6955-09-5
N-{(S)-1-Benzyl-2-[(Z)-hydroxyimino]-propyl}-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / 4-dimethylaminopyridine / triethylamine / 20 - 40 °C

2: 91 percent / NaOAc / H₂O / 2 h / 60 - 80 °C

With dmap; sodium acetate; In water; triethylamine;
DOI:10.1016/S0040-4039(01)82927-0

Reference yield:

: 6955-09-5
N-{(S)-1-Benzyl-2-[(Z)-hydroxyimino]-propyl}-acetamide

: 1722-84-5,18793-45-8,18793-44-7
(E)-N-styrylacetamide

: 1722-84-5,18793-44-7,18793-45-8
(Z)-N-styrylacetamide

Guidance literature:: With triethylamine; p-toluenesulfonyl chloride; In acetonitrile; at -10 - 20 ℃; for 2h; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(01)82927-0