Methyl 10-chloro-9-hydroxyoctadecanoate

Base Information

• Chemical Name: Methyl 10-chloro-9-hydroxyoctadecanoate
• CAS No.: 10411-46-8
• Molecular Formula: C₁₉H₃₇ClO₃
• Molecular Weight: 348.954
• DSSTox Substance ID: DTXSID10908801
• Nikkaji Number: J2.165.367E
• Mol file: 10411-46-8.mol

Synonyms:Methyl 10-chloro-9-hydroxyoctadecanoate;10-Chloro-9-hydroxyoctadecanoic acid methyl ester;10411-46-8;Octadecanoic acid, 10-chloro-9-hydroxy-, methyl ester;C19H37ClO3;DTXSID10908801

Chemical Property of Methyl 10-chloro-9-hydroxyoctadecanoate

Chemical Property:

• Vapor Pressure: 3.68E-09mmHg at 25°C
• Boiling Point: 429°Cat760mmHg
• Flash Point: 213.3°C
• PSA: 46.53000
• Density: 0.982g/cm³
• LogP: 5.60900
• XLogP3: 6.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 17
• Exact Mass: 348.2431227
• Heavy Atom Count: 23
• Complexity: 271

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCC(C(CCCCCCCC(=O)OC)O)Cl

Technology Process of Methyl 10-chloro-9-hydroxyoctadecanoate

There total 13 articles about Methyl 10-chloro-9-hydroxyoctadecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-9,10-epoxyoctadecanoic acid methyl ester (2500-59-6,2566-91-8,6084-76-0,38003-69-9,38003-75-7,38003-77-9,79854-41-4,112244-28-7) → Methyl-threo-10-chlor-9-hydroxyoctadecanoat (6064-72-8,10411-46-8,13985-35-8)

Guidance literature:

With hydrogenchloride; diethyl ether;

DOI:10.1021/ja01115a025

Reference yield:

Methyl oleate (112-62-9) → Methyl-threo-10-chlor-9-hydroxyoctadecanoat (6064-72-8,10411-46-8,13985-35-8)

Guidance literature:

Multi-step reaction with 2 steps

1: peroxyacetic acid; acetic acid

2: hydrogen chloride; diethyl ether

With hydrogenchloride; peracetic acid; diethyl ether; acetic acid;

DOI:10.1021/ja01115a025

Reference yield:

(Z)-9,10-epoxyoctadecanoic acid methyl ester (2500-59-6,2566-91-8,6084-76-0,38003-69-9,38003-75-7,38003-77-9,79854-41-4,112244-28-7) → methyl 10-chloro-9-hydroxyoctadecanoate (10411-46-8) + methyl 9-chloro-10-hydroxyoctadecanoate (22348-93-2)

Guidance literature:

With chloro-trimethyl-silane; triethylamine; In dichloromethane; at 55 ℃;

upstream raw materials:

diazomethane

(+/-)-threo-10-chloro-9-hydroxy-octadecanoic acid

(Z)-9,10-epoxyoctadecanoic acid methyl ester

cis-9,10-epoxystearic acid