Merucathinone

Base Information

Chemical Name:Merucathinone
CAS No.:107638-80-2
Molecular Formula:C₁₁H₁₃NO
Molecular Weight:175.23
Hs Code.:
Nikkaji Number:J630.730B

Synonyms:Merucathinone;(+)-Merucathinone;107638-80-2;(E,4S)-4-amino-1-phenylpent-1-en-3-one;AKOS040736370

Suppliers and Price of Merucathinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Merucathinone

Chemical Property:

Vapor Pressure:0.000995mmHg at 25°C
Boiling Point:302.4°Cat760mmHg
Flash Point:136.7°C
Density:1.064g/cm³
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:175.099714038
Heavy Atom Count:13
Complexity:192

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)C=CC1=CC=CC=C1)N
Isomeric SMILES:C[C@@H](C(=O)/C=C/C1=CC=CC=C1)N

Technology Process of Merucathinone

There total 3 articles about Merucathinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (R)-N-(1-Methyl-2-oxo-4-phenylbut-3-enyl)carbamidsaeure-(tert-butyl)ester

: 107638-80-2
(E)-(R)-4-Amino-1-phenyl-pent-1-en-3-one

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 0.333333h;
DOI:10.1002/hlca.19860690621

Reference yield:

: (S)-N-(1-Methyl-2-oxo-4-phenylbut-3-enyl)carbamidsaeure-(tert-butyl)ester

: 107638-80-2
(S)-4-amino-1-phenylpent-1-en-3-on

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 0.333333h;
DOI:10.1002/hlca.19860690621

Reference yield:

: 4843-72-5,6160-69-6,62839-69-4
(E)-2-phenylethenyllithium

: 107638-80-2
(S)-4-amino-1-phenylpent-1-en-3-on

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) BuLi/hexane / 1.) THF/Et₂O/pentane 66/17/17, -78 deg C to 65 deg C, 15 min, 2.) THF/Et₂O/pentane, -120 deg C to -90 deg C, 30 min then 1 h, 20 deg C

2: CF₃COOH / CH₂Cl₂ / 0.33 h

With n-butyllithium; hexane; trifluoroacetic acid; In dichloromethane;
DOI:10.1002/hlca.19860690621