(2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid

Base Information

Chemical Name:(2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid
CAS No.:664366-07-8
Molecular Formula:C16H14O5
Molecular Weight:286.27900
Hs Code.:
Mol file:664366-07-8.mol

Synonyms:2-(2,3,5-trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetic acid;(2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)-acetic acid;

Suppliers and Price of (2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid
500mg
$ 237.00

Crysdot
2-(2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)aceticacid 97%
5g
$ 752.00

Total 4 raw suppliers

Chemical Property of (2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid

Chemical Property:

Melting Point:255 - 256 °C (propan-2-ol)
PSA：80.65000
LogP:3.09150

Purity/Quality:

98%min ^*data from raw suppliers

(2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid

There total 4 articles about (2,3,5-Trimethyl-7-oxo-7H-furo[3,2-g]-chromen-6-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 664365-87-1
methyl 2-[4-methyl-7-(1-methyl-2-oxopropoxy)-2-oxo-2H-3-chromenyl]acetate

: 664366-07-8
(2',3',5'-trimethyl-7'-oxo-7H-furo[3,2-g][1]benzopyran-6'-yl)acetic acid

Guidance literature:: methyl 2-[4-methyl-7-(1-methyl-2-oxopropoxy)-2-oxo-2H-3-chromenyl]acetate; With sodium hydroxide; In isopropyl alcohol; for 3h; Heating;

With sulfuric acid; In isopropyl alcohol;
DOI:10.1023/A:1025466317733

Reference yield:

: 95903-37-0
7-hydroxy-3-methoxycarbonylmethyl-4-methyl-2H-chromen-2-one

: 664366-07-8
(2',3',5'-trimethyl-7'-oxo-7H-furo[3,2-g][1]benzopyran-6'-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: 84 percent / K₂CO₃ / acetone / 50 - 56 °C

2.1: aq. NaOH / propan-2-ol / 3 h / Heating

2.2: 87 percent / aq. H₂SO₄ / propan-2-ol

With sodium hydroxide; potassium carbonate; In isopropyl alcohol; acetone; 1.1: Williamson reaction;
DOI:10.1023/A:1025466317733

Reference yield:

: 10420-33-4
dimethyl 2-acetylsuccinate

: 664366-07-8
(2',3',5'-trimethyl-7'-oxo-7H-furo[3,2-g][1]benzopyran-6'-yl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: 60 percent / HCl / methanol / 3 h / 0 °C

2.1: 84 percent / K₂CO₃ / acetone / 50 - 56 °C

3.1: aq. NaOH / propan-2-ol / 3 h / Heating

3.2: 87 percent / aq. H₂SO₄ / propan-2-ol

With hydrogenchloride; sodium hydroxide; potassium carbonate; In methanol; isopropyl alcohol; acetone; 1.1: Pechmann condensation / 2.1: Williamson reaction;
DOI:10.1023/A:1025466317733