D:C-Friedoolean-8-en-3-one

Base Information

• Chemical Name: D:C-Friedoolean-8-en-3-one
• CAS No.: 22611-26-3
• Molecular Formula: C₃₀H₄₈O
• Molecular Weight: 424.711
• Mol file: 22611-26-3.mol

Synonyms:D:C-Friedoolean-8-en-3-one(7CI,8CI); 3(2H)-Picenone,1,4,4a,5,6,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14b-octadecahydro-4,4,6b,8a,11,11,12b,14b-octamethyl-,(4aR,6bS,8aR,12aR,12bS,14bS)-; Isomultiflorenone; [4aR-(4aa,6bb,8ab,12ab,12ba,14bb)]-1,4,4a,5,6,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14b-Octadecahydro-4,4,6b,8a,11,11,12b,14b-octamethyl-3(2H)-picenone

Chemical Property of D:C-Friedoolean-8-en-3-one

Chemical Property:

• PSA: 17.07000
• LogP: 8.52120

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of D:C-Friedoolean-8-en-3-one

There total 14 articles about D:C-Friedoolean-8-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

alnus-5(10)-en-3β-ol (63043-86-7) → Isomultiflorenon (22611-26-3)

Guidance literature:

Multi-step reaction with 6 steps

1: m-chloroperbenzoic acid; Na₂HPO_4. 12 H₂O / CHCl₃ / 4 h / 0 °C

2: 95 percent / pyridine / 14 h / Ambient temperature

3: 81.4 mg / BF_3.OEt₂ / benzene / 0.5 h / Ambient temperature

4: 40 mg / hydrogen / 5percent Pd/C / ethyl acetate / 72 h

5: 13 mg / 5percent KOH / methanol; tetrahydrofuran / 24 h / Ambient temperature

6: 16 mg / Collins reagent / 0.27 h / Ambient temperature

With pyridine; potassium hydroxide; disodium hydrogenphosphate; Collins oxidation agent; boron trifluoride diethyl etherate; hydrogen; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; chloroform; ethyl acetate; benzene;

DOI:10.1246/bcsj.58.185

Reference yield:

alnus-5(10)-en-3β-yl acetate (6449-21-4) → Isomultiflorenon (22611-26-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 97 percent / m-chloroperbenzoic acid; Na₂HPO_4.12 H₂O / CHCl₃ / 7 h / 0 °C

2: 81.4 mg / BF_3.OEt₂ / benzene / 0.5 h / Ambient temperature

3: 40 mg / hydrogen / 5percent Pd/C / ethyl acetate / 72 h

4: 13 mg / 5percent KOH / methanol; tetrahydrofuran / 24 h / Ambient temperature

5: 16 mg / Collins reagent / 0.27 h / Ambient temperature

With potassium hydroxide; disodium hydrogenphosphate; Collins oxidation agent; boron trifluoride diethyl etherate; hydrogen; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; chloroform; ethyl acetate; benzene;

DOI:10.1246/bcsj.58.185

Reference yield:

dendropanoxide (5957-66-4) → Isomultiflorenon (22611-26-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 2) pyridine

2: 97 percent / m-chloroperbenzoic acid; Na₂HPO_4.12 H₂O / CHCl₃ / 7 h / 0 °C

3: 81.4 mg / BF_3.OEt₂ / benzene / 0.5 h / Ambient temperature

4: 40 mg / hydrogen / 5percent Pd/C / ethyl acetate / 72 h

5: 13 mg / 5percent KOH / methanol; tetrahydrofuran / 24 h / Ambient temperature

6: 16 mg / Collins reagent / 0.27 h / Ambient temperature

With pyridine; potassium hydroxide; disodium hydrogenphosphate; Collins oxidation agent; boron trifluoride diethyl etherate; hydrogen; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; chloroform; ethyl acetate; benzene;

DOI:10.1246/bcsj.58.185

upstream raw materials:

isomultiflorenyl acetate

D:C-friedo-olean-8-en-3β-ol

alnus-5(10)-en-3β-ol

alnus-5(10)-en-3β-yl acetate