Butanedioic acid, 2-hydroxy-, sodium salt (1:2), (2S)-

Base Information

• Chemical Name: Butanedioic acid, 2-hydroxy-, sodium salt (1:2), (2S)-
• CAS No.: 138-09-0
• Molecular Formula: C₄H₄O₅*2Na
• Molecular Weight: 178.052
• Hs Code.: 2918199090
• European Community (EC) Number: 205-313-8
• Mol file: 138-09-0.mol

Synonyms:Butanedioic acid, 2-hydroxy-, sodium salt (1:2), (2S)-;138-09-0;L-(-)-Malic acid disodium salt;L-(-)-Malic acid sodium salt, 95-100% (enzymatic)

Chemical Property of Butanedioic acid, 2-hydroxy-, sodium salt (1:2), (2S)-

Chemical Property:

• Appearance/Colour: white to slightly off-white crystalline powder
• Boiling Point: 306.4 °C at 760 mmHg
• Flash Point: 153.4 °C
• PSA: 100.49000
• Density: g/cm³
• LogP: -3.76280
• Storage Temp.: Store at RT.
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 157.01129257
• Heavy Atom Count: 10
• Complexity: 129

Purity/Quality:

98%,99%, ^*data from raw suppliers

L-(?)-Malic acid sodium salt 95-100% (enzymatic) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(C(=O)O)O)C(=O)O.[Na]
• Isomeric SMILES: C([C@@H](C(=O)O)O)C(=O)O.[Na]

Technology Process of Butanedioic acid, 2-hydroxy-, sodium salt (1:2), (2S)-

There total 3 articles about Butanedioic acid, 2-hydroxy-, sodium salt (1:2), (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.4%

sodium maleate (3105-55-3,5873-57-4,7704-73-6,17013-01-3,18016-19-8,30915-61-8,44670-32-8,54060-75-2,72383-56-3,371-47-1) → disodium L-malate (138-09-0,676-46-0,3105-51-9,20786-58-7,22798-10-3,40520-93-2,51209-20-2,57467-17-1,58214-38-3,63441-17-8,68303-40-2,97251-45-1,129283-54-1)

Guidance literature:

With Alcaligenes sp. T₅₀₁; In water; toluene; at 40 ℃; for 4h; Product distribution; Variation of pH and time; also with organic acids; further bacteria;

Reference yield:

4-ethoxy-3-hydroxy-4-oxobutanoic acid (71901-42-3) → sodium malate (138-09-0,676-46-0,3105-51-9,20786-58-7,22798-10-3,40520-93-2,51209-20-2,57467-17-1,58214-38-3,63441-17-8,68303-40-2,97251-45-1,129283-54-1)

Guidance literature:

With water; sodium hydroxide; for 0.00555556h; pH=12.9;

Reference yield:

(2R)-2-phenylpropylamine malate → (R)-2-phenylpropylamine (582-22-9,17596-79-1,28163-64-6,45789-52-4) + disodium L-malate (138-09-0,676-46-0,3105-51-9,20786-58-7,22798-10-3,40520-93-2,51209-20-2,57467-17-1,58214-38-3,63441-17-8,68303-40-2,97251-45-1,129283-54-1)

Guidance literature:

With sodium hydroxide; In dichloromethane; water; at 20 ℃; for 1h;

upstream raw materials:

4-ethoxy-3-hydroxy-4-oxobutanoic acid

sodium maleate

Downstream raw materials:

Oxalacetic acid