2-thiothenoic acid

Base Information

• Chemical Name: 2-thiothenoic acid
• CAS No.: 49628-34-4
• Molecular Formula: C5H4 O S2
• Molecular Weight: 144.218
• Mol file: 49628-34-4.mol

Synonyms:2-thiothenoic acid

Chemical Property of 2-thiothenoic acid

Chemical Property:

• Vapor Pressure: 0.051mmHg at 25°C
• Boiling Point: 235.2°Cat760mmHg
• Flash Point: 96°C
• PSA: 80.56000
• Density: 1.335g/cm³
• LogP: 1.98160

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-thiothenoic acid

There total 2 articles about 2-thiothenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-Thiophenecarbonyl chloride (5271-67-0) → thiophene-2-monocarboxylic acid (49628-34-4)

Guidance literature:

With potassium hydroxide; hydrogen sulfide; In ethanol; for 1h; cooling with NaCl/ice;

Reference yield:

2-thiophenylcarboxylic acid (527-72-0) → thiophene-2-monocarboxylic acid (49628-34-4)

Guidance literature:

With Lawessons reagent; In acetonitrile; at 100 ℃; for 0.25h; Inert atmosphere; Microwave irradiation;

DOI:10.1016/j.ejmech.2017.04.015

Reference yield: 90.0%

platensimycin + thiophene-2-monocarboxylic acid (49628-34-4) → C29H31NO8S2

Guidance literature:

With caesium carbonate; In dichloromethane; at 20 ℃; for 12h;

upstream raw materials:

2-Thiophenecarbonyl chloride

2-thiophenylcarboxylic acid

Downstream raw materials:

Mo₂(2,4,6-triisopropylbenzoate)2(2-thienylthiocarboxylate)2

W₂(2,4,6-triisopropylbenzoate)2(2-thienylthiocarboxylate)2

H[(triphenylphosphine)2Cu(thiophene-2-thiocarboxylate)2]