2-Hydrazinyl-3-(4-methoxyphenyl)quinazolin-4-one

Base Information

Chemical Name:2-Hydrazinyl-3-(4-methoxyphenyl)quinazolin-4-one
CAS No.:66679-68-3
Molecular Formula:C15H14N4O2
Molecular Weight:282.302
Hs Code.:
DSSTox Substance ID:DTXSID00361507
Nikkaji Number:J276.972G
Wikidata:Q82143848

Synonyms:2-hydrazinyl-3-(4-methoxyphenyl)quinazolin-4-one;Oprea1_806317;66679-68-3;SCHEMBL6276607;DTXSID00361507;2-Hydrazino-3-(4-methoxyphenyl)quinazolin-4(3H)-one

Suppliers and Price of 2-Hydrazinyl-3-(4-methoxyphenyl)quinazolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Hydrazinyl-3-(4-methoxyphenyl)quinazolin-4-one

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:282.11167570
Heavy Atom Count:21
Complexity:418

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3N=C2NN

Technology Process of 2-Hydrazinyl-3-(4-methoxyphenyl)quinazolin-4-one

There total 10 articles about 2-Hydrazinyl-3-(4-methoxyphenyl)quinazolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1031-88-5
2-sulfhydryl-3-(4-methoxyphenyl)-quinazolin-4(3H)-one

: 66679-68-3
2-hydrazino-3-(4-methoxyphenyl)-quinazolin-4(3H)-one

Guidance literature:: With hydrazine hydrate; In ethanol; at 100 ℃; for 1.5h;
DOI:10.1002/jhet.440

Reference yield: 78.0%

: 1035-55-8
2-methylsulfanyl-3-(4-methoxyphenyl)-quinazolin-4(3H)-one

: 66679-68-3
2-hydrazino-3-(4-methoxyphenyl)-quinazolin-4(3H)-one

Guidance literature:: With potassium carbonate; hydrazine; In ethanol; for 36h;
DOI:10.1134/S1068162021010246

Reference yield:

: 1031-88-5
3‐(4‐methoxyphenyl)‐2‐thioxo‐2,3‐dihydroquinazolin‐4(1H)‐one

: 66679-68-3
2-hydrazino-3-(4-methoxyphenyl)-quinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / NaOH / ethanol / 1 h

2: 74 percent / hydrazine hydrate; K₂CO₃ / ethanol / 30 h / Heating

With sodium hydroxide; potassium carbonate; hydrazine hydrate; In ethanol;
DOI:10.1248/cpb.55.76