7-Azabicyclo[2.2.1]heptane, 7-[2-[4-[2-[3-(4-acetyl-1-piperazinyl)-1-pyrrolidinyl]ethyl]-5-(3,5-dimethyl phenyl)-6H-thieno[2,3-b]pyrrol-2-yl]-2-methyl-1-oxopropyl]-

Base Information

• Chemical Name: 7-Azabicyclo[2.2.1]heptane, 7-[2-[4-[2-[3-(4-acetyl-1-piperazinyl)-1-pyrrolidinyl]ethyl]-5-(3,5-dimethyl phenyl)-6H-thieno[2,3-b]pyrrol-2-yl]-2-methyl-1-oxopropyl]-
• CAS No.: 666852-45-5
• Molecular Formula: C36H49N5O2S
• Molecular Weight: 615.883

Synonyms:

Chemical Property of 7-Azabicyclo[2.2.1]heptane, 7-[2-[4-[2-[3-(4-acetyl-1-piperazinyl)-1-pyrrolidinyl]ethyl]-5-(3,5-dimethyl phenyl)-6H-thieno[2,3-b]pyrrol-2-yl]-2-methyl-1-oxopropyl]-

Chemical Property:

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Technology Process of 7-Azabicyclo[2.2.1]heptane, 7-[2-[4-[2-[3-(4-acetyl-1-piperazinyl)-1-pyrrolidinyl]ethyl]-5-(3,5-dimethyl phenyl)-6H-thieno[2,3-b]pyrrol-2-yl]-2-methyl-1-oxopropyl]-

There total 1 articles about 7-Azabicyclo[2.2.1]heptane, 7-[2-[4-[2-[3-(4-acetyl-1-piperazinyl)-1-pyrrolidinyl]ethyl]-5-(3,5-dimethyl phenyl)-6H-thieno[2,3-b]pyrrol-2-yl]-2-methyl-1-oxopropyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

1-(4-pyrrolidin-3-yl-piperazin-1-yl)ethanone (666853-72-1) + 2-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-4-(2-chloroethyl)-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole (666852-79-5) → 2-[1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1]heptan-7-ylethyl]-4-[2-(3-(4-acetylpiperazin-1-yl)pyrrolidin-1-yl)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole (666852-45-5)

Guidance literature:

With potassium carbonate; sodium iodide; In ISOPROPYLAMIDE; at 85 ℃; for 4h;

upstream raw materials:

1-(4-pyrrolidin-3-yl-piperazin-1-yl)ethanone

2-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-4-(2-chloroethyl)-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole

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