3,5,6,7-Tetrahydro-5-((dimethylamino)methylene)-2-ethyl-3-oxo-2H-2-pyrindine-4-carbonitrile

Base Information

Chemical Name:3,5,6,7-Tetrahydro-5-((dimethylamino)methylene)-2-ethyl-3-oxo-2H-2-pyrindine-4-carbonitrile
CAS No.:128767-23-7
Molecular Formula:C₁₄H₁₇N₃O
Molecular Weight:243.308
Hs Code.:
Wikidata:Q76279214

Synonyms:BRN 4190005;2H-2-Pyrindine-4-carbonitrile, 3,5,6,7-tetrahydro-5-((dimethylamino)methylene)-2-ethyl-3-oxo-;3,5,6,7-Tetrahydro-5-((dimethylamino)methylene)-2-ethyl-3-oxo-2H-2-pyrindine-4-carbonitrile;128767-23-7;LS-136372

Suppliers and Price of 3,5,6,7-Tetrahydro-5-((dimethylamino)methylene)-2-ethyl-3-oxo-2H-2-pyrindine-4-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3,5,6,7-Tetrahydro-5-((dimethylamino)methylene)-2-ethyl-3-oxo-2H-2-pyrindine-4-carbonitrile

Chemical Property:

Vapor Pressure:2.64E-07mmHg at 25°C
Boiling Point:421.3°C at 760 mmHg
Flash Point:208.6°C
Density:1.18g/cm³
XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:243.137162174
Heavy Atom Count:18
Complexity:529

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C=C2CCC(=CN(C)C)C2=C(C1=O)C#N
Isomeric SMILES:CCN1C=C2CC/C(=C\N(C)C)/C2=C(C1=O)C#N

Technology Process of 3,5,6,7-Tetrahydro-5-((dimethylamino)methylene)-2-ethyl-3-oxo-2H-2-pyrindine-4-carbonitrile

There total 3 articles about 3,5,6,7-Tetrahydro-5-((dimethylamino)methylene)-2-ethyl-3-oxo-2H-2-pyrindine-4-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 128767-19-1
N-Ethyl-4-cyano-5,6-dihydro-7H-cyclopenta<1,2-c>pyridin-3-one

: 1188-33-6
N,N-dimethylformamide diethyl diacetal

: 128767-23-7
N-Ethyl-4-cyano-5-N',N'-dimethylaminomethylene-2,3,5,6-tetrahydro-7H-cyclopenta<1,2-c>pyridin-3-one

Guidance literature:: In toluene; for 4h; Heating;
DOI:10.1007/BF00499413

Reference yield: 16.0%

: 88745-35-1
4-Cyano-2,3,5,6-tetrahydro-7H-cyclopenta<1,2-c>pyridin-3-one

: 1188-33-6
N,N-dimethylformamide diethyl diacetal

: 128767-21-5
5-Cyano-5-N,N-dimethylaminomethylene-2,3,5,6-tetrahydro-7H-cyclopenta<1,2-c>pyridin-3-one

: 128767-23-7
N-Ethyl-4-cyano-5-N',N'-dimethylaminomethylene-2,3,5,6-tetrahydro-7H-cyclopenta<1,2-c>pyridin-3-one

Guidance literature:: In ethanol; for 3.5h; Heating;
DOI:10.1007/BF00499413

Reference yield:

: 88745-35-1
4-Cyano-2,3,5,6-tetrahydro-7H-cyclopenta<1,2-c>pyridin-3-one

: 128767-23-7
N-Ethyl-4-cyano-5-N',N'-dimethylaminomethylene-2,3,5,6-tetrahydro-7H-cyclopenta<1,2-c>pyridin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1) NaOEt / 1) EtOH, 55-60 deg C

2: 68 percent / toluene / 4 h / Heating

With sodium ethanolate; In toluene;
DOI:10.1007/BF00499413