Gabapentin Related Compound E (10 mg) (carboxymethyl-cyclohexanecarboxylic acid)

Base Information

• Chemical Name: Gabapentin Related Compound E (10 mg) (carboxymethyl-cyclohexanecarboxylic acid)
• CAS No.: 667465-00-1
• Molecular Formula: C9H14O4
• Molecular Weight: 186.20500
• Hs Code.: 2918990090
• Mol file: 667465-00-1.mol

Synonyms:Cyclohexanecarboxylic acid,carboxymethyl ester;

Chemical Property of Gabapentin Related Compound E (10 mg) (carboxymethyl-cyclohexanecarboxylic acid)

Chemical Property:

• Boiling Point: 323.1±25.0 °C(Predicted)
• PKA: 2.65±0.10(Predicted)
• PSA: 63.60000
• Density: 1.199±0.06 g/cm3(Predicted)
• LogP: 1.19450
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-?((Cyclohexanecarbony?l)?oxy)?aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-?((Cyclohexanecarbony?l)?oxy)?acetic Acid (Gabapentin EP Impurity E; Gabapentin USP Related Compound E) is a metabolite of Gabapentin (G117250), amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.

Technology Process of Gabapentin Related Compound E (10 mg) (carboxymethyl-cyclohexanecarboxylic acid)

There total 1 articles about Gabapentin Related Compound E (10 mg) (carboxymethyl-cyclohexanecarboxylic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

2-cyclohexyl-1,3-dioxolane (4362-48-5) → cyclohexanecarboxylic acid carboxymethyl ester (667465-00-1)

Guidance literature:

With sodium hypochlorite; cis-{RuCl₂(Me₂SO)4}; In ethyl acetate; at 20 ℃; for 5h; pH=9.5;

DOI:10.1002/adsc.200303124

upstream raw materials:

2-cyclohexyl-1,3-dioxolane

Refernces