N-(2-Methoxy-5-nitrophenyl)acetamide

Base Information

• Chemical Name: N-(2-Methoxy-5-nitrophenyl)acetamide
• CAS No.: 33721-54-9
• Molecular Formula: C9H10 N2 O4
• Molecular Weight: 210.189
• Hs Code.: 2924299090
• European Community (EC) Number: 251-656-1
• NSC Number: 107596
• DSSTox Substance ID: DTXSID7067792
• Nikkaji Number: J154.694E
• Wikidata: Q81994445
• Mol file: 33721-54-9.mol

Synonyms:N-(2-Methoxy-5-nitrophenyl)acetamide;33721-54-9;Acetamide, N-(2-methoxy-5-nitrophenyl)-;o-Acetaniside, 5'-nitro-;o-Acetanisidide, 5'-nitro-;ACETAMIDE,N-(2-METHOXY-5-NITROPHENYL)-;EINECS 251-656-1;NSC 107596;N-(2-Methoxy-5-nitrophenyl) acetamide;NSC107596;2-acetamido-4-nitroanisole;Cambridge id 5172744;SCHEMBL2502044;2'-Methoxy-5'-nitroacetanilide;DTXSID7067792;BBL023281;MFCD00035892;STL293567;AKOS002813553;NSC-107596;2-Acetylamino-4-nitro-1-methoxybenzene;VS-07378;N-[2-(Methyloxy)-5-nitrophenyl]acetamide;E10140;AB00074840-01;AE-848/05730047;SR-01000197541;SR-01000197541-1

Chemical Property of N-(2-Methoxy-5-nitrophenyl)acetamide

Chemical Property:

• Vapor Pressure: 2.26E-06mmHg at 25°C
• Boiling Point: 392.6°Cat760mmHg
• Flash Point: 191.2°C
• PSA: 84.15000
• Density: 1.327g/cm³
• LogP: 2.15800
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 210.06405680
• Heavy Atom Count: 15
• Complexity: 251

Purity/Quality:

99% ^*data from raw suppliers

N-(2-METHOXY-5-NITROPHENYL)ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=C(C=CC(=C1)[N+](=O)[O-])OC

Technology Process of N-(2-Methoxy-5-nitrophenyl)acetamide

There total 16 articles about N-(2-Methoxy-5-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.48%

2-methoxy-5-nitroaniline hydrochloride (67827-72-9) + acetic anhydride (108-24-7) → N-(2-methoxy-5-nitrophenyl)acetamide (33721-54-9)

Guidance literature:

at 80 ℃; for 8h;

Reference yield: 90.0%

3-amino-4-methoxynitrobenzene (99-59-2) → N-(2-methoxy-5-nitrophenyl)acetamide (33721-54-9)

Guidance literature:

With acetic acid; In water;

Reference yield: 90.0%

acetic acid (64-19-7,77671-22-8) + 3-amino-4-methoxynitrobenzene (99-59-2) → N-(2-methoxy-5-nitrophenyl)acetamide (33721-54-9)

Guidance literature:

In water; at 20 ℃; for 1.5h;

upstream raw materials:

2-methoxyacetanilide

acetic anhydride

3-amino-4-methoxynitrobenzene

methyl bromide

Downstream raw materials:

N-(5-amino-2-methoxyphenyl)-acetamide

acetic acid-(2-methoxy-4,5-dinitro-anilide)

3-amino-4-methoxynitrobenzene

2-methoxy-5-nitro-diacetanilide