ALPHA-PANASINSENE

Base Information

• Chemical Name: ALPHA-PANASINSENE
• CAS No.: 56633-28-4
• Molecular Formula: C₁₅H₂₄
• Molecular Weight: 204.356
• Mol file: 56633-28-4.mol

Synonyms:α-Panasinsen;α-panasinsene;

Chemical Property of ALPHA-PANASINSENE

Chemical Property:

• Boiling Point: 256.5±7.0 °C(Predicted)
• Flash Point: 100 °C
• PSA: 0.00000
• Density: 0.890 g/mL at 20 °C(lit.)
• LogP: 4.55910

Purity/Quality:

Safty Information:

• Safety Statements: 23-24/25

MSDS Files:

Useful:

Technology Process of ALPHA-PANASINSENE

There total 3 articles about ALPHA-PANASINSENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.1%

β-caryophyllene (87-44-5) → β-caryolanol (58404-89-0,82008-48-8,129445-45-0,472-97-9) + isocaryolan-8-ol (131717-65-2) + (-)-isocaryophyllene (118-65-0) + (-)-α-panasinsen (56633-28-4,77286-73-8)

Guidance literature:

With sulfuric acid; In diethyl ether; at 0 - 20 ℃; for 0.5h; Yield given. Further byproducts given;

DOI:10.1021/ja00141a009

Reference yield:

(2aS,4aR,8R,8aS)-2,2,4a,,8-tetramethyldecahydrocyclobutinden-8-ol (80374-27-2) → α-neoclovene (4545-68-0) + (-)-α-panasinsen (56633-28-4,77286-73-8) + β-panasinsene (56684-97-0)

Guidance literature:

With pyridine; thionyl chloride; for 0.166667h; Title compound not separated from byproducts;

DOI:10.1021/ja00141a009

Reference yield:

methyllithium (917-54-4) + (2aR,4aS,8aR)-2,2,4a-Trimethyl-octahydro-cyclobuta[c]inden-8-one (15355-35-8,34175-65-0,77286-71-6) → β-panasinsene (56684-97-0,77286-72-7,80951-32-2,83648-26-4) + α-panasinsene (56633-28-4,77286-73-8)

Guidance literature:

With pyridine; thionyl chloride; Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1016/0040-4039(80)80104-3

upstream raw materials:

methyllithium

(2aR,4aS,8aR)-2,2,4a-Trimethyl-octahydro-cyclobuta[c]inden-8-one

β-caryophyllene

(2aS,4aR,8R,8aS)-2,2,4a,,8-tetramethyldecahydrocyclobutinden-8-ol

Refernces

• 1、 McMurry, John E.,Choy, William. "TOTAL SYNTHESIS OF α- AND β-PANASINSENE". . p. 2477 - 2480. Retrieved 2007/10/02.