Besipirdine

Base Information

Chemical Name:Besipirdine
CAS No.:119257-34-0
Molecular Formula:C₁₆H₁₇N₃
Molecular Weight:251.331
Hs Code.:
UNII:95PY16J933
DSSTox Substance ID:DTXSID50152361
Nikkaji Number:J556.652E
Wikipedia:Besipirdine
Wikidata:Q4896297
NCI Thesaurus Code:C171657
Pharos Ligand ID:XQN5TWNAMHRR
ChEMBL ID:CHEMBL29835
Mol file:119257-34-0.mol

Synonyms:besipirdine;besipirdine hydrochloride;HP 749;HP-749;N-(n-propyl)-N-(4-pyridinyl)-1H-indol-1-amine hydrochloride

Suppliers and Price of Besipirdine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
Besipirdine
5 mg
$ 950.00

American Custom Chemicals Corporation
BESIPIRDINE 95.00%
5MG
$ 503.58

Total 2 raw suppliers

Chemical Property of Besipirdine

Chemical Property:

Vapor Pressure:8.49E-07mmHg at 25°C
Boiling Point:405.9°Cat760mmHg
PKA:7.94±0.10(Predicted)
Flash Point:199.3°C
PSA：21.06000
Density:1.09g/cm³
LogP:3.71600
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:251.142247555
Heavy Atom Count:19
Complexity:275

Purity/Quality:

95% ^*data from raw suppliers

Besipirdine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN(C1=CC=NC=C1)N2C=CC3=CC=CC=C32
Uses Alzheimer’s disease treatment (cognition enhancer).

Technology Process of Besipirdine

There total 4 articles about Besipirdine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 120-72-9
indole

: 119257-34-0
N-propyl-N-(4-pyridinyl)-1H-indol-1-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) potassium hydroxide, 2.) hydroxylamine O-sulfonic acid / 1.) DMF, 2.) DMF, RT, 1 h

2: 50 percent / propan-2-ol / 2 h / 80 °C

3: 1.) sodium hydride / 1.) DMF, 1 h, 2.) DMF, RT, 1 h

With potassium hydroxide; sodium hydride; hydroxylamine-O-sulfonic acid; In isopropyl alcohol;
DOI:10.1021/jm9506433

Reference yield:

: 53406-38-5
1H-indol-1-amine

: 119257-34-0
N-propyl-N-(4-pyridinyl)-1H-indol-1-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / propan-2-ol / 2 h / 80 °C

2: 1.) sodium hydride / 1.) DMF, 1 h, 2.) DMF, RT, 1 h

With sodium hydride; In isopropyl alcohol;
DOI:10.1021/jm9506433