Octadecanamide

Base Information

• Chemical Name: Octadecanamide
• CAS No.: 124-26-5
• Deprecated CAS: 37189-35-8,176201-41-5,176201-41-5
• Molecular Formula: C18H37NO
• Molecular Weight: 283.498
• Hs Code.: DERIVATION
• European Community (EC) Number: 204-693-2
• NSC Number: 66462
• UNII: YQX129FH1U
• DSSTox Substance ID: DTXSID9027025
• Nikkaji Number: J43.334I
• Wikidata: Q27116315
• Metabolomics Workbench ID: 4493
• ChEMBL ID: CHEMBL88311
• Mol file: 124-26-5.mol

Synonyms:Stearamide(6CI,7CI,8CI);Adogen 42;Advawax 290;Alflow S 10;Amide AP;Amide S;Amide S (binder);Amide T;Armid 18;Armoslip 18LF;Atmer SA 1750;Crodamide S;Crodamide SR;Diamid AP 1;EBF;Fatty Amide S;Fatty Amide T;G 270;Hidorin F792;Hidorin M 7;Hymicron G 270;Hymicron L 271;Kao Fatty Amide S;KawaslipVL;Kemamide S;L 271;Lutamide S;NSC 66462;Neutron 2;Neutron 2S;Selosol 2M;Stearic acid amide;Stearic amide;Stearoylamide;Stearoylamine;Stearylamide;Uniwax 1750;Stearamide;

Chemical Property of Octadecanamide

Chemical Property:

• Appearance/Colour: light yellow granules
• Vapor Pressure: 7.11E-07mmHg at 25°C
• Melting Point: 98-102 °C(lit.)
• Refractive Index: 1.432-1.434
• Boiling Point: 408.2 °C at 760 mmHg
• PKA: 16.61±0.40(Predicted)
• Flash Point: 207.5 °C
• PSA: 43.09000
• Density: 0.868 g/cm³
• LogP: 6.43350
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly, Sonicated), Methanol (Slightly)
• Water Solubility.: 102μg/L at 20℃
• XLogP3: 6.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 16
• Exact Mass: 283.287514804
• Heavy Atom Count: 20
• Complexity: 204

Purity/Quality:

99% ^*data from raw suppliers

Octadecanamide ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Stearates
• Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)N
• Uses: Corrosion inhibitor in oil wells.

Technology Process of Octadecanamide

There total 28 articles about Octadecanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.4%

stearic acid (57-11-4) → stearamide (124-26-5)

Guidance literature:

With titanium(IV) isopropylate; ammonia; at 165 ℃; for 7h; Reagent/catalyst; Temperature; Large scale;

Reference yield: 97.0%

Octadecanoyl-carbamic acid tert-butyl ester (120158-01-2) → stearamide (124-26-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; for 1h; Ambient temperature;

Reference yield: 95.0%

octadecanoyl azide (77165-65-2) → stearamide (124-26-5)

Guidance literature:

With zinc(II) tetrahydroborate; In 1,2-dimethoxyethane; for 0.5h; Ambient temperature;

DOI:10.1021/jo00094a021

upstream raw materials:

stearic acid ethyl ester

(stearoylamino-methylsulfanyl)-acetic acid

formamide

stearic acid

Downstream raw materials:

N-stearoyl-N'-phenylurea

N-(4-methoxy-benzyl)-stearamide

N-stearoylglycine

N-stearoyliminodiacetic acid

Refernces

• 1、 Yadav, Suman,Reshi, Noor U Din,Pal, Saikat,Bera, Jitendra K.. "Aerobic oxidation of primary amines to amides catalyzed by an annulated mesoionic carbene (MIC) stabilized Ru complex". . p. 7018 - 7028. Retrieved 2021/11/17.
• 2、 Jamil, Md. A. R.,Siddiki, S. M. A. Hakim,Touchy, Abeda Sultana,Rashed, Md. Nurnobi,Poly, Sharmin Sultana,Jing, Yuan,Ting, Kah Wei,Toyao, Takashi,Maeno, Zen,Shimizu, Ken-ichi. "Selective Transformations of Triglycerides into Fatty Amines, Amides, and Nitriles by using Heterogeneous Catalysis". . p. 3115 - 3125. Retrieved 2019/04/26.