Cycloastragenol

Base Information

Chemical Name:Cycloastragenol
CAS No.:78574-94-4
Molecular Formula:C₃₀H₅₀O₅
Molecular Weight:490.724
Hs Code.:2942000000
European Community (EC) Number:846-798-1
UNII:X37D9F2L0V
ChEMBL ID:CHEMBL4171632
DSSTox Substance ID:DTXSID301029686
Metabolomics Workbench ID:65580,198899
Nikkaji Number:J427.606J
Wikidata:Q3979404
Wikipedia:Cycloastragenol
Mol file:78574-94-4.mol

Synonyms:astramembrangenin;cycloastragenol;cyclogalegigenin;GRN510

Suppliers and Price of Cycloastragenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Cycloastragenol
100mg
$ 125.00

TCI Chemical
Cycloastragenol
25mg
$ 23.00

TCI Chemical
Cycloastragenol
100mg
$ 63.00

Sigma-Aldrich
Cycloastragenol phyproof?ReferenceSubstance
10 mg
$ 393.12

CSNpharm
Cycloastragenol
25mg
$ 61.00

CSNpharm
Cycloastragenol
250mg
$ 109.00

CSNpharm
Cycloastragenol
1g
$ 274.00

Crysdot
Cycloastragenol 97%
5g
$ 832.00

Crysdot
Cycloastragenol 97%
1g
$ 277.00

Chem-Impex
Cycloastragenol,99%(HPLC) 99%(HPLC)
250MG
$ 67.20

Total 77 raw suppliers

Chemical Property of Cycloastragenol

Chemical Property:

Melting Point:241.0 to 245.0 °C
Boiling Point:617.174 °C at 760 mmHg
PKA:14.57±0.29(Predicted)
Flash Point:327.055 °C
PSA：90.15000
Density:1.2 g/cm³
LogP:4.43660
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:4.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:490.36582469
Heavy Atom Count:35
Complexity:916

Purity/Quality:

99% ^*data from raw suppliers

Cycloastragenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(CCC23C1C(CC4C2(C3)CCC5(C4(CC(C5C6(CCC(O6)C(C)(C)O)C)O)C)C)O)O)C
Isomeric SMILES:C[C@]12CC[C@@]34C[C@@]35CC[C@@H](C([C@@H]5[C@H](C[C@H]4[C@@]1(C[C@@H]([C@@H]2[C@]6(CC[C@H](O6)C(C)(C)O)C)O)C)O)(C)C)O
Recent ClinicalTrials:Telomerase Activator and Retinal Amyloid
Recent EU Clinical Trials:Telomerase ACTivator to reverse Immunosenescence in Acute Coronary Syndrome: a double-blind, phase II, pilot randomised controlled trial (TACTIC)

Technology Process of Cycloastragenol

There total 48 articles about Cycloastragenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 83207-58-3,84687-43-4
astragaloside IV

: 84605-18-5,90865-25-1,104112-00-7,78574-94-4
cycloastragenol

Guidance literature:: With hydrogenchloride; In methanol; at 20 ℃; for 168h;

Reference yield: 4.0%

: 83207-58-3,84687-43-4
astragaloside IV

: 20R,24S-epoxy-3β,16β,25-trihydroxy-9β-methyl-19-norlanost-1,5-diene

: 84605-18-5,90865-25-1,104112-00-7,78574-94-4
cycloastragenol

: 86541-83-5
cyclosieversigenin 3-O-β-D-xylopyranoside

: 86764-12-7
cyclosieversigenin 6-O-β-D-glucopyranoside

Guidance literature:: With sulfuric acid; In methanol; for 1.5h; Reflux;

Reference yield:

: 84676-89-1
(3b,6a,16b,20R,24S)-3-((2-O-acetyl-beta-D-xylopyranosyl)oxy)-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl beta-D-glucopyranoside

: 84605-18-5,90865-25-1,104112-00-7,78574-94-4
cycloastragenol

Guidance literature:: Multi-step reaction with 2 steps

1: 19 mg / 1.) 10 percent sodium methoxide; 2.) Dowex 50w*8(H⁺) / methanol / 0.25 h / Heating

2: 30 mg / aq. 10 percent hydrogen chloride / ethanol; benzene / 24 h / Heating

With hydrogenchloride; Dowex 50w*8(H⁺); sodium methylate; In methanol; ethanol; benzene;
DOI:10.1248/cpb.31.698