1,2,4-Triazolo(4,3-a)pyridine, 6-(4-(2,5-difluorophenyl)-5-oxazolyl)-3-(1-methylethyl)-

Base Information

Chemical Name:1,2,4-Triazolo(4,3-a)pyridine, 6-(4-(2,5-difluorophenyl)-5-oxazolyl)-3-(1-methylethyl)-
CAS No.:668981-02-0
Molecular Formula:C18H14F2N4O
Molecular Weight:340.332
Hs Code.:
UNII:FG7DYB4F07
DSSTox Substance ID:DTXSID0047294
Wikidata:Q27277970
Pharos Ligand ID:3RTCH1L5N5H9
ChEMBL ID:CHEMBL379866

Synonyms:CP-863187;668981-02-0;FG7DYB4F07;UNII-FG7DYB4F07;CP-281384;DTXSID0047294;1,2,4-Triazolo(4,3-a)pyridine, 6-(4-(2,5-difluorophenyl)-5-oxazolyl)-3-(1-methylethyl)-;6-(4-(2,5-Difluorophenyl)-1,3-oxazol-5-yl)-3-isopropyl(1,2,4)triazolo(4,3-a)pyridine;1,2,4-Triazolo[4,3-a]pyridine, 6-[4-(2,5-difluorophenyl)-5-oxazolyl]-3-(1-methylethyl)-;4-(2,5-Difluorophenyl)-5-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxazole;CHEMBL379866;SCHEMBL4762527;DTXCID8027294;BDBM16342;UACOXBQBNWQWOK-UHFFFAOYSA-N;Tox21_300457;triazolopyridine oxazole inhibitor 12;AKOS040748168;NCGC00248059-01;NCGC00254362-01;CAS-668981-02-0;CP-863187, >=98% (HPLC);Q27277970;6-[4-(2,5-difluoro-phenyl)-oxazol-5-yl]-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine;4-(2,5-difluorophenyl)-5-(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-1,3-oxazole;4-(2,5-difluorophenyl)-5-[3-(propan-2-yl)-[1,2,4]triazolo[3,4-a]pyridin-6-yl]-1,3-oxazole

Suppliers and Price of 1,2,4-Triazolo(4,3-a)pyridine, 6-(4-(2,5-difluorophenyl)-5-oxazolyl)-3-(1-methylethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2,4-Triazolo(4,3-a)pyridine, 6-(4-(2,5-difluorophenyl)-5-oxazolyl)-3-(1-methylethyl)-

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:340.11356741
Heavy Atom Count:25
Complexity:468

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C1=NN=C2N1C=C(C=C2)C3=C(N=CO3)C4=C(C=CC(=C4)F)F

Technology Process of 1,2,4-Triazolo(4,3-a)pyridine, 6-(4-(2,5-difluorophenyl)-5-oxazolyl)-3-(1-methylethyl)-

There total 2 articles about 1,2,4-Triazolo(4,3-a)pyridine, 6-(4-(2,5-difluorophenyl)-5-oxazolyl)-3-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 668981-02-0
6-[4-(2,5-difluoro-phenyl)-oxazol-5-yl]-3-isopropyl-[1,2,4] triazolo [4,3-a] pyridine

Guidance literature:: Purification / work up;

Reference yield: 40.6%

: 668981-09-7
6-[4-BROMO-OXAZOL-5-YL]-3-ISOPROPYL-[1,2,4]TRIAZOLO[4,3-a]PYRIDINE

: 193353-34-3
2,5-difurorboronic acid

: 668981-02-0
6-[4-(2,5-difluoro-phenyl)-oxazol-5-yl]-3-isopropyl-[1,2,4] triazolo [4,3-a] pyridine

Guidance literature:: With triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In H₂₀; ethanol; at 65 - 70 ℃; Cooling with acetone-dry ice;