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10-formyldihydrofolate

Base Information
  • Chemical Name:10-formyldihydrofolate
  • CAS No.:28459-40-7
  • Molecular Formula:C20H21 N7 O7
  • Molecular Weight:471.42
  • Hs Code.:
  • Mol file:28459-40-7.mol
10-formyldihydrofolate

Synonyms:Glutamicacid, N-[p-[N-[(2-amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]formamido]benzoyl]-(8CI); L-Glutamic acid,N-[4-[[(2-amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-(9CI); 10-Formyl-7,8-dihydrofolic acid; N-Formyl-7,8-dihydrofolic acid

Suppliers and Price of 10-formyldihydrofolate
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Medical Isotopes, Inc.
  • 10-Formyl-7,8-dihydroFolicAcid(>85%)DisodiumSalt
  • 50 mg
  • $ 2400.00
  • American Custom Chemicals Corporation
  • FOLIC ACID IMPURITY-F 95.00%
  • 5MG
  • $ 500.98
Total 10 raw suppliers
Chemical Property of 10-formyldihydrofolate
Chemical Property:
  • Boiling Point:°Cat760mmHg 
  • PKA:3.38±0.10(Predicted) 
  • Flash Point:°C 
  • PSA:221.16000 
  • Density:1.67g/cm3 
  • LogP:0.50370 
Purity/Quality:

99% *data from raw suppliers

10-Formyl-7,8-dihydroFolicAcid(>85%)DisodiumSalt *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses 10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells.
Technology Process of 10-formyldihydrofolate

There total 3 articles about 10-formyldihydrofolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium hydroxide; oxygen;
DOI:10.1021/ja01151a028
Guidance literature:
With coenzyme-A; enzyme-substance from clostridium sticklandii; 2-oxo-propionic acid;
DOI:10.1016/0006-3002(58)90484-0
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