Chemical Property of Fexinidazole
Chemical Property:
- Vapor Pressure:4.58E-10mmHg at 25°C
- Boiling Point:511.3°C at 760 mmHg
- Flash Point:263.1°C
- PSA：98.17000
- Density:1.33g/cm3
- LogP:3.15240
- Storage Temp.:Sealed in dry,Room Temperature
- XLogP3:2.5
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:4
- Exact Mass:279.06776246
- Heavy Atom Count:19
- Complexity:305
- Purity/Quality:
-
99%, *data from raw suppliers
1-Methyl-2-((4-(methylthio)phenoxy)-methyl)-5-nitro-1H-imidazole 95+% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CN1C(=CN=C1COC2=CC=C(C=C2)SC)[N+](=O)[O-]
- Recent ClinicalTrials:A Pharmacokinetic and Tolerability Study of Fexinidazole in a Single Oral Dose in Adult Participants With Mild and Moderate Hepatic Impairment
- Recent EU Clinical Trials:Phase 2 Randomized, Multicenter, Double-blinded Safety and Efficacy Study to Evaluate Oral Fexinidazole Dosing Regimens for the Treatment of Adult Patients with Chronic Indeterminate Chagas Disease
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Uses
Fexinidazole is a medication used in the treatment of African trypanosomiasis caused by trypanosoma brucei gambiense. An antitrypanosomal agent. It also functions as a medication used against the main species that cause visceral and cutaneous new World leishmaniasis.
