2,3-Dioxo-5-indolinesulfonic acid

Base Information

• Chemical Name: 2,3-Dioxo-5-indolinesulfonic acid
• CAS No.: 7313-70-4
• Molecular Formula: C8H5 N O5 S
• Molecular Weight: 227.197
• European Community (EC) Number: 230-773-1
• UNII: NCY7M68CQ6
• DSSTox Substance ID: DTXSID20223395
• Nikkaji Number: J212.307J
• Wikidata: Q72509149
• ChEMBL ID: CHEMBL2228492
• Mol file: 7313-70-4.mol

Synonyms:2,3-dioxo-5-indolinesulfonic acid

Chemical Property of 2,3-Dioxo-5-indolinesulfonic acid

Chemical Property:

• Melting Point: 143℃
• PSA: 108.92000
• Density: 1.743
• LogP: 1.28690
• Storage Temp.: 2-8°C
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 226.98884343
• Heavy Atom Count: 15
• Complexity: 409

Purity/Quality:

97% ^*data from raw suppliers

2,3-Dioxoindoline-5-sulfonicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1S(=O)(=O)O)C(=O)C(=O)N2

Technology Process of 2,3-Dioxo-5-indolinesulfonic acid

There total 9 articles about 2,3-Dioxo-5-indolinesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) → isatin-5-monosulphonic acid (7313-70-4)

Guidance literature:

With fuming sulphuric acid; 1.) 0 deg C, 5 min, 2.) from 0 deg C to 70 deg C, 15 min;

Reference yield:

indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) → isatin-5-monosulphonic acid (7313-70-4) + 3,3-dichloro-2-oxo-indoline-5-sulfonic acid (750561-55-8)

Guidance literature:

With chlorosulfonic acid; at 70 ℃; for 3h; Inert atmosphere; Cooling with ice;

DOI:10.1016/j.bmc.2013.11.028

Reference yield:

indigo-5,5'-disulfonic acid (483-20-5) → isatin-5-monosulphonic acid (7313-70-4)

Guidance literature:

With sodium periodate; cetyltrimethylammonim bromide; In hexane; chloroform; water; at 30.84 ℃; Concentration; Kinetics;

upstream raw materials:

indole-2,3-dione

chloral hydrate

4-aminobenzene sulfonic acid

C_.I_. Acid Blue 74

Downstream raw materials:

chloranil

4-hydroxy-benzaldehyde

(Z)-3-(2-(2-nitrophenyl)hydrazono)-2-oxoindoline-5-sulfonic acid

5-chlorosulfonylisatin