Butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine

Base Information

Chemical Name:Butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine
CAS No.:66556-73-8
Molecular Formula:C₄₄H₅₉N₅O₈
Molecular Weight:785.981
Hs Code.:
DSSTox Substance ID:DTXSID30216738
Nikkaji Number:J2.649.423K
Wikidata:Q83093028
ChEMBL ID:CHEMBL3311030

Synonyms:BOC-Phe-Leu-Phe-Leu-Phe;Boc2 cpd;BPLPLP;butyloxycarbonyl-Phe-Leu-Phe-Leu-Phe;butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine;N-t-Boc-Phe-DLeu-Phe-DLeu-Phe;N-t-Boc-Phe-Leu-Phe-Leu-Phe;N-tertiary-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine

Suppliers and Price of Butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH
10 mg
$ 142.00

Biosynth Carbosynth
Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH
50 mg
$ 492.00

Biosynth Carbosynth
Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH
250 mg
$ 1860.00

American Custom Chemicals Corporation
BOC-PHE-D-LEU-PHE-D-LEU-PHE-OH 98.00%
0.1G
$ 1375.00

AK Scientific
Butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine
10mg
$ 241.00

Total 11 raw suppliers

Chemical Property of Butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1043.2 °C at 760 mmHg
PKA:3.51±0.10(Predicted)
Flash Point:584.7 °C
PSA：192.03000
Density:1.167 g/cm³
LogP:6.67830
Storage Temp.:-15°C
XLogP3:6.6
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:22
Exact Mass:785.43636386
Heavy Atom Count:57
Complexity:1300

Purity/Quality:

99% ^*data from raw suppliers

Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CC3=CC=CC=C3)NC(=O)OC(C)(C)C
Isomeric SMILES:CC(C)C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)OC(C)(C)C

Technology Process of Butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine

There total 16 articles about Butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1261486-37-6
Boc-Phe-Leu-Phe-Leu-Phe-O-t-Bu

: 66556-73-8,148182-34-7
N-tert-butyloxycarbonyl-Phe-Leu-Phe-Leu-Phe

Guidance literature:: With cross-linked enzyme aggregates of Alcalase; water; In 1,4-dioxane; at 37 ℃; for 37h; Enzymatic reaction;
DOI:10.1002/adsc.201000313

Reference yield:

: 16937-99-8,53296-34-7
N-Boc-D-Leu

: 66556-73-8,148182-34-7
Boc-FL(D)FL(D)F

Guidance literature:: Multi-step reaction with 6 steps

1: EDCI; HOBt / dimethylformamide / 0 °C

2: 1 N aq. NaOH

3: EDCI; HOBt / dimethylformamide / 0 °C

4: HCl / dioxane / 20 °C

5: EDCI; HOBt / dimethylformamide / 0 °C

6: 1 N aq. NaOH

With hydrogenchloride; sodium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; N,N-dimethyl-formamide; 1: Condensation / 2: saponification / 3: Condensation / 4: acidolysis / 5: Condensation / 6: saponification;

Reference yield:

: 87976-66-7
Boc-D-Leu-Phe-OMe

: 66556-73-8,148182-34-7
Boc-FL(D)FL(D)F

Guidance literature:: Multi-step reaction with 5 steps

1: 1 N aq. NaOH

2: EDCI; HOBt / dimethylformamide / 0 °C

3: HCl / dioxane / 20 °C

4: EDCI; HOBt / dimethylformamide / 0 °C

5: 1 N aq. NaOH

With hydrogenchloride; sodium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; N,N-dimethyl-formamide; 1: saponification / 2: Condensation / 3: acidolysis / 4: Condensation / 5: saponification;