Crenolanib besylate

Base Information

Chemical Name:Crenolanib besylate
CAS No.:670220-93-6
Molecular Formula:C26H29N5O2.C6H6O3S
Molecular Weight:601.726
Hs Code.:
UNII:MC4B01024K
ChEMBL ID:CHEMBL2146086
NCI Thesaurus Code:C106204
Wikidata:Q27283841

Synonyms:CRENOLANIB BESYLATE;670220-93-6;Crenolanib besilate;Crenolanib besylate [USAN];ARO-002-26;CP-868,596-26;MC4B01024K;1-(2-(5-((3-Methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine benzenesulfonate;CP-868596-26;Crenolanib besylate (USAN);4-Piperidinamine, 1-(2-(5-((3-methyl-3-oxetanyl)methoxy)-1H-benzimidazol-1-yl)-8- quinolinyl)-, benzenesulfonate (1:1);CP868596;1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1H-1,3-benzodiazol-1-yl}quinolin-8-yl)piperidin-4-amine;benzenesulfonic acid;4-Piperidinamine, 1-(2-(5-((3-methyl-3-oxetanyl)methoxy)-1H-benzimidazol-1-yl)-8-quinolinyl)-, benzenesulfonate (1:1);4-Piperidinamine,1-[2-[5-[(3-methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-, monobenzenesulfonate;1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine;CP-868;UNII-MC4B01024K;SCHEMBL4681285;CHEMBL2146086;ARQUTWAXTHJROR-UHFFFAOYSA-N;BCP24113;CRENOLANIB BESILATE [WHO-DD];AKOS032947280;SB16604;D10103;Q27283841;1-(2-(5-((3-Methyloxetan-3-yl)methoxy)-1H-benzimidazol-1-yl)quinolin-8-yl)piperidin-4- amine monobenzenesulfonate;1-(2-(5-((3-Methyloxetan-3-yl)methoxy)-1H-benzimidazol-1-yl)quinolin-8-yl)piperidin-4-amine monobenzenesulfonate;1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine. PhSO3H;1-{2-[5-(3-Methyl-oxetan-3-ylmethoxy)-benzoimidazol-1-yl]-quinolin-8-yl}-piperidin-4-ylamine benzenesulfonate

Suppliers and Price of Crenolanib besylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of Crenolanib besylate

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:6
Exact Mass:601.23589041
Heavy Atom Count:43
Complexity:851

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(COC1)COC2=CC3=C(C=C2)N(C=N3)C4=NC5=C(C=CC=C5N6CCC(CC6)N)C=C4.C1=CC=C(C=C1)S(=O)(=O)O
Recent ClinicalTrials:Study of Crenolanib Combined With Chemotherapy in FLT3-mutated Acute Myeloid Leukemia Patients
Recent EU Clinical Trials:Phase III Randomized, Double-blind, Placebo-controlled Study Investigating the Efficacy of the Addition of Crenolanib to Salvage Chemotherapy Versus Salvage Chemotherapy Alone in Subjects ≤ 75 Years of Age with Relapsed/Refractory FLT3 Mutated Acute Myeloid Leukemia

Technology Process of Crenolanib besylate

There total 1 articles about Crenolanib besylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%