Cycloheptanecarboxamide

Base Information

• Chemical Name: Cycloheptanecarboxamide
• CAS No.: 1459-39-8
• Molecular Formula: C8H15NO
• Molecular Weight: 141.213
• Hs Code.: 2924299090
• Mol file: 1459-39-8.mol

Synonyms:cycloheptanecarboxamide

Chemical Property of Cycloheptanecarboxamide

Chemical Property:

• Vapor Pressure: 0.00155mmHg at 25°C
• Melting Point: 193-194 °C(Solv: ethanol (64-17-5))
• Refractive Index: 1.478
• Boiling Point: 295.2 °C at 760 mmHg
• PKA: 16.76±0.20(Predicted)
• Flash Point: 132.3 °C
• PSA: 44.08000
• Density: 0.99 g/cm³
• LogP: 2.59180
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Cycloheptanecarboxamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cycloheptanecarboxamide

There total 8 articles about Cycloheptanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

cycloheptanecarbonitrile (32730-85-1) → cycloheptanecarboxamide (1459-39-8)

Guidance literature:

With copper(l) iodide; caesium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In nitromethane; water; at 20 - 100 ℃; for 3h;

DOI:10.1055/s-0037-1609912

Reference yield:

cycloheptanoic acid (1460-16-8) → cycloheptanecarboxamide (1459-39-8)

Guidance literature:

With phosphorus pentachloride; Behandeln des Reaktionsgemisches mit konz. Ammoniak;

Reference yield:

cycloheptanecarbonyl chloride (6557-86-4) → cycloheptanecarboxamide (1459-39-8)

Guidance literature:

With ammonium hydroxide;

upstream raw materials:

cycloheptanoic acid

cycloheptanecarbonyl chloride

cyclohept-1-enecarboxylic acid

Cyclohepta-1,3-dien-1-carbonsaeure

Downstream raw materials:

cycloheptanamine

cycloheptylmethylamine

cycloheptanecarbonitrile

Cycloheptylamine hydrochloride

Refernces

• 1、 Kuwabara, Jun,Sawada, Yoshiharu,Yoshimatsu, Mitsuhiro. "Nitrile Hydration Reaction Using Copper Iodide/Cesium Carbonate/DBU in Nitromethane-Water". supporting information. p. 2061 - 2065. Retrieved 2018/09/14.